{"id":"W4409822191","doi":"10.1158/1538-7445.am2025-ct094","title":"Abstract CT094: Durvalumab (D) vs placebo (P) after concurrent chemoradiotherapy (cCRT) in limited-stage small-cell lung cancer (LS-SCLC): Outcomes by PD-L1 expression in ADRIATIC","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Durvalumab; Medicine; Oncology; Internal medicine; Stage (stratigraphy); Chemoradiotherapy; Placebo; Cancer; Pathology; Immunotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001927557,0.0005268767,0.001213098,0.001215067,0.0001888444,0.000130306,0.0006431382,0.0002989079,0.002136181],"category_scores_gemma":[0.0005004543,0.0004391272,0.0001919397,0.001745668,0.0004343746,0.0001954931,0.0004529551,0.002281477,0.00003260968],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005307956,"about_ca_system_score_gemma":0.002380344,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007948315,"about_ca_topic_score_gemma":0.007421459,"domain_scores_codex":[0.9941517,0.0004620376,0.0008711116,0.00119122,0.001515984,0.001807961],"domain_scores_gemma":[0.997241,0.0009135465,0.0001304225,0.0009073471,0.0004193855,0.0003883069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008014832,0.001131907,0.7944107,0.006164618,0.0003604201,0.000423671,0.003571368,0.000124117,0.08026955,0.00002600556,0.09635685,0.009145962],"study_design_scores_gemma":[0.03564249,0.0004345779,0.7771078,0.01013007,0.00008903124,0.000002130712,0.001261029,0.001447487,0.09923765,0.00004014224,0.07359403,0.001013521],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9216259,0.06184535,0.00001803572,0.00916447,0.0005136695,0.003765681,0.0002022269,0.00007879902,0.002785938],"genre_scores_gemma":[0.951291,0.02031675,0.00006850521,0.0008452338,0.0001866554,0.006924857,0.00003437443,0.0001028589,0.02022979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0415286,"threshold_uncertainty_score":0.999806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04740485122507896,"score_gpt":0.4421369264632889,"score_spread":0.3947320752382099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}