{"id":"W4409822415","doi":"10.1158/1538-7445.am2025-ct022","title":"Abstract CT022: Divarasib plus migoprotafib combination treatment in patients with <i>KRAS G12C</i>-positive non-small cell lung cancer (NSCLC)","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada); Princess Margaret Cancer Centre; Ottawa Hospital; University Health Network","funders":"","keywords":"Medicine; KRAS; Cancer; Internal medicine; Lung cancer; Oncology; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001824144,0.0005672597,0.0008806126,0.0002583023,0.0003091204,0.0005203092,0.0003925627,0.0003553468,0.00373779],"category_scores_gemma":[0.0001778297,0.0001626377,0.0003642383,0.000403228,0.0002336822,0.0002983425,0.0001982893,0.0008132697,0.0006696861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006944471,"about_ca_system_score_gemma":0.0008488274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001168674,"about_ca_topic_score_gemma":0.004097593,"domain_scores_codex":[0.9999185,0.00001960401,0.000008106466,0.00001896331,0.00001604656,0.00001880105],"domain_scores_gemma":[0.9998846,0.000009281606,0.00002194051,0.000005333593,0.00001124946,0.00006764563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2556284,0.009563895,0.05822203,0.00147748,0.00135899,0.002645073,0.0003153996,0.004104141,0.1772726,0.000469445,0.0254269,0.4635157],"study_design_scores_gemma":[0.1621279,0.4954781,0.2137277,0.0003027283,0.002093413,0.01076927,0.0003071456,0.007581525,0.0530669,0.0003863363,0.05400331,0.0001556726],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870662,0.004289814,0.0002780766,0.0003848514,0.00007315356,0.0003657772,0.001021966,0.0001146424,0.006405439],"genre_scores_gemma":[0.9931898,0.001195585,0.0005455213,0.0002796526,0.0001001788,0.0001939524,0.002080134,0.00001246159,0.002402756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00373779,"threshold_uncertainty_score":0.0125041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02211388574136848,"score_gpt":0.3929362772389591,"score_spread":0.3708223914975907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}