{"id":"W4409825064","doi":"10.3389/fnins.2025.1563607","title":"Voluntary running partially prevents photoreceptor cell death in retinitis pigmentosa","year":2025,"lang":"en","type":"article","venue":"Frontiers in Neuroscience","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Innovation and Technology Commission","keywords":"Retinitis pigmentosa; Neuroscience; Biology; Retina","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001923157,0.0001251858,0.0001179798,0.0001439996,0.00005845663,0.00002907989,0.0003313114,0.0000701032,0.000004310494],"category_scores_gemma":[0.00007951671,0.0001357202,0.00003520645,0.0003487166,0.00008665366,0.00001047413,0.0001437567,0.0001009525,0.000001292116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002861966,"about_ca_system_score_gemma":0.0001383175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002877221,"about_ca_topic_score_gemma":0.0000262726,"domain_scores_codex":[0.9988199,0.00005016085,0.000216759,0.0004581409,0.0001365217,0.0003184947],"domain_scores_gemma":[0.9997185,0.000004339071,0.00004611429,0.0001729757,0.00001237558,0.00004562837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007299035,0.00006839404,0.8784442,0.00001418193,0.000001069066,0.00001032379,0.00005323308,0.00007206797,0.111499,0.000009349083,0.009099191,0.0006560134],"study_design_scores_gemma":[0.001163842,0.0001677683,0.7761248,0.00009316628,0.000004482794,0.000001767525,0.0001724036,0.001254003,0.1473818,0.0003086721,0.07297995,0.0003473211],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887915,0.0003937137,0.003314715,0.0001114454,0.001302565,0.0002197755,0.000002883937,0.000008168043,0.005855254],"genre_scores_gemma":[0.9929152,0.0005350056,0.003239661,0.0008450508,0.00001705507,0.00003653358,0.00001614185,0.000007820185,0.002387501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1023194,"threshold_uncertainty_score":0.553451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00704231659754035,"score_gpt":0.2370947431709521,"score_spread":0.2300524265734118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}