{"id":"W4409826979","doi":"10.1111/cyt.13503","title":"Malignancy Risk, Molecular Mutations, and Surgical Outcomes of Thyroid Nodules Classified as Atypia of Undetermined Significance in the Bethesda System: A Comprehensive Analysis","year":2025,"lang":"en","type":"article","venue":"Cytopathology","topic":"Thyroid Cancer Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University; McGill University Health Centre","funders":"","keywords":"Medicine; Atypia; Thyroid nodules; Malignancy; Surgical pathology; Thyroid; Thyroid carcinoma; Cytopathology; Pathology; Thyroid neoplasm; Radiology; Cytology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007598433,0.0001769956,0.0002763586,0.001522734,0.0002377248,0.0004213879,0.0003098968,0.0002853699,0.0007938959],"category_scores_gemma":[0.001785078,0.0001976539,0.0004153164,0.001038967,0.000213535,0.0003915122,0.0005337745,0.000184259,0.0001984892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003184716,"about_ca_system_score_gemma":0.0002815362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002977631,"about_ca_topic_score_gemma":0.003954598,"domain_scores_codex":[0.9995036,0.00007722592,0.00008319684,0.0001261964,0.0001468898,0.00006284772],"domain_scores_gemma":[0.9988453,0.0002058037,0.000554688,0.00009145338,0.0001717299,0.0001310379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003710396,0.000006148822,0.998409,0.000007607197,0.00003840595,0.00003539489,0.00002400238,0.00003809363,0.0001428188,0.000006567909,0.0000317718,0.00122318],"study_design_scores_gemma":[0.00000135533,0.00002773622,0.9992085,0.000005483856,0.00003294379,0.0003356655,0.00008149757,0.0001551926,0.00004418704,0.000009529362,0.0000957297,0.00000220169],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998657,0.0005862098,0.00009228661,0.00001160716,0.000001314437,0.000006905639,0.0003929185,0.00000420461,0.0002475294],"genre_scores_gemma":[0.9991695,0.0001352167,0.00006087144,0.000004220515,0.000004166498,0.000004918313,0.00056831,0.00000138167,0.00005145574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002977631,"threshold_uncertainty_score":0.005920589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01120771414192408,"score_gpt":0.3000956230066019,"score_spread":0.2888879088646778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}