{"id":"W4409826979","doi":"10.1111/cyt.13503","title":"Malignancy Risk, Molecular Mutations, and Surgical Outcomes of Thyroid Nodules Classified as Atypia of Undetermined Significance in the Bethesda System: A Comprehensive Analysis","year":2025,"lang":"en","type":"article","venue":"Cytopathology","topic":"Thyroid Cancer Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University; McGill University Health Centre","funders":"","keywords":"Medicine; Atypia; Thyroid nodules; Malignancy; Surgical pathology; Thyroid; Thyroid carcinoma; Cytopathology; Pathology; Thyroid neoplasm; Radiology; Cytology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002033911,0.0001414894,0.0007842433,0.0002805911,0.00003469684,0.000004910734,0.00009694966,0.0000919731,0.000006285033],"category_scores_gemma":[0.00007356324,0.00009384577,0.0001770446,0.0005341329,0.000236529,0.00001558191,0.00003384412,0.0001118077,0.000001461489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005066961,"about_ca_system_score_gemma":0.00007398194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003434769,"about_ca_topic_score_gemma":0.00009920886,"domain_scores_codex":[0.9986302,0.0003758923,0.000442094,0.0002748091,0.0001326793,0.0001443599],"domain_scores_gemma":[0.9986713,0.0006052311,0.0002180126,0.0003768733,0.00009864887,0.00002993386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002296111,0.0003008409,0.9784189,0.0002172409,0.000594582,0.0008184024,0.0005994624,0.00007717908,0.004486814,0.01315265,0.00001352547,0.001090835],"study_design_scores_gemma":[0.002251295,0.0003351768,0.9878598,0.0001024582,0.001880752,0.00005813581,0.001414908,0.00009908653,0.005520871,0.0003584249,0.00004964299,0.00006938],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935164,0.00442725,0.0001807153,0.0007054543,0.00004065167,0.0004492078,0.0000482775,0.00001196375,0.0006200045],"genre_scores_gemma":[0.9990837,0.0003300345,0.0002688711,0.0001229208,0.000005822456,0.0001158325,0.00002247834,0.000006350637,0.00004401486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01279422,"threshold_uncertainty_score":0.3826919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01120771414192408,"score_gpt":0.3000956230066019,"score_spread":0.2888879088646778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}