{"id":"W4409852646","doi":"10.1002/pros.24905","title":"Primary Analysis of (NCT03380806) a Phase II Randomized Trial of Stereotactic Body Radiotherapy Boost Versus Conventional Fractionation External Beam Radiotherapy Boost in Unfavorable‐Intermediate and High‐Risk Prostate Cancer","year":2025,"lang":"en","type":"article","venue":"The Prostate","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; Impact; Niagara Health System; McMaster University; Juravinski Cancer Centre","funders":"Sanofi","keywords":"Medicine; External beam radiotherapy; Prostate cancer; Brachytherapy; Urology; Dose fractionation; Radiation therapy; Androgen deprivation therapy; Prostate; Clinical endpoint; Randomized controlled trial; Internal medicine; Oncology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004088442,0.002692023,0.003578722,0.0005943791,0.0007484743,0.001592926,0.001411245,0.002132959,0.0410048],"category_scores_gemma":[0.003775743,0.0008784098,0.003115071,0.0007852098,0.0009578619,0.001098865,0.0006593318,0.003535164,0.004546511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001410688,"about_ca_system_score_gemma":0.002394332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001639639,"about_ca_topic_score_gemma":0.005872105,"domain_scores_codex":[0.9984422,0.0009720399,0.00008404141,0.0002352131,0.0001035613,0.0001629378],"domain_scores_gemma":[0.9987175,0.0003459913,0.0003650568,0.0001161606,0.0001397473,0.0003154766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9762947,0.003234153,0.0004010952,0.001903415,0.001796301,0.00003559069,0.00003831561,0.0003520272,0.001098862,0.0002543381,0.00588165,0.008709626],"study_design_scores_gemma":[0.9818394,0.01473579,0.0006185636,0.00007719108,0.0006206738,0.00001794677,0.00001014865,0.0001667507,0.0001351468,0.0002198139,0.001550639,0.000007818097],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7048135,0.02993771,0.005299145,0.006513027,0.006420836,0.1378891,0.06035722,0.001443415,0.04732612],"genre_scores_gemma":[0.8347456,0.007261527,0.004941302,0.007239355,0.001866336,0.1012055,0.01591849,0.0001791988,0.02664268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0410048,"threshold_uncertainty_score":0.1371747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01005604840096012,"score_gpt":0.3170136921189361,"score_spread":0.306957643717976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}