{"id":"W4409852646","doi":"10.1002/pros.24905","title":"Primary Analysis of (NCT03380806) a Phase II Randomized Trial of Stereotactic Body Radiotherapy Boost Versus Conventional Fractionation External Beam Radiotherapy Boost in Unfavorable‐Intermediate and High‐Risk Prostate Cancer","year":2025,"lang":"en","type":"article","venue":"The Prostate","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; Impact; Niagara Health System; McMaster University; Juravinski Cancer Centre","funders":"Sanofi","keywords":"Medicine; External beam radiotherapy; Prostate cancer; Brachytherapy; Urology; Dose fractionation; Radiation therapy; Androgen deprivation therapy; Prostate; Clinical endpoint; Randomized controlled trial; Internal medicine; Oncology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001248553,0.000311546,0.001442843,0.0006607826,0.0001348286,0.00003460809,0.0001206868,0.00008382218,0.0001747216],"category_scores_gemma":[0.0001372803,0.0002162436,0.000376487,0.0008222971,0.0004111701,0.0001989797,0.00004614927,0.0002665466,4.107746e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005448482,"about_ca_system_score_gemma":0.0004679183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001830307,"about_ca_topic_score_gemma":0.0001202198,"domain_scores_codex":[0.9973168,0.0003681547,0.001115924,0.0004403258,0.0004539089,0.0003048888],"domain_scores_gemma":[0.9973694,0.0009773771,0.0009592611,0.0003747408,0.0002304568,0.00008876771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9417577,0.002325923,0.01731894,0.0002114279,0.009399286,0.00001513235,0.001889924,0.000409897,0.004556716,0.0002003516,0.0001409144,0.02177378],"study_design_scores_gemma":[0.9412802,0.003224334,0.03722606,0.0004687358,0.005031057,0.000002592769,0.00007262512,0.005555667,0.005902487,0.0004599425,0.000572726,0.0002035536],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823331,0.01028569,0.0003650678,0.001563272,0.0005867125,0.004177985,0.0005851685,0.00003045084,0.0000725329],"genre_scores_gemma":[0.9495148,0.04794036,0.0002135436,0.0002710834,0.00008136801,0.001066487,0.0002491982,0.00002942083,0.000633757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03765466,"threshold_uncertainty_score":0.881816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01005604840096012,"score_gpt":0.3170136921189361,"score_spread":0.306957643717976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}