{"id":"W4409869110","doi":"10.1093/sleep/zsaf112","title":"Sex differences in cerebrospinal fluid proteomics of patients with restless legs syndrome","year":2025,"lang":"en","type":"article","venue":"SLEEP","topic":"Restless Legs Syndrome Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Surgical Specialties (Canada)","funders":"","keywords":"Cerebrospinal fluid; Proteomics; Restless legs syndrome; Body mass index; Sex characteristics; Pathophysiology; Case-control study; Immune system; Medicine; Biology; Internal medicine; Immunology; Bioinformatics; Gene; Neuroscience; Neurology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003023095,0.0002784652,0.00032249,0.0005414527,0.0002179613,0.000472934,0.0001172441,0.0002313238,0.001367635],"category_scores_gemma":[0.0009138506,0.00009456996,0.000213115,0.0003852713,0.000183318,0.0002329814,0.0002505821,0.0001791045,0.000224502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001177912,"about_ca_system_score_gemma":0.0001166719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004157077,"about_ca_topic_score_gemma":0.0003692977,"domain_scores_codex":[0.999772,0.00004312597,0.00003449476,0.00007271476,0.00004206265,0.00003559388],"domain_scores_gemma":[0.9995916,0.00007257224,0.0002111527,0.00002380768,0.00004759295,0.00005331347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006345257,0.00004168614,0.9869185,0.00003374887,0.0000959669,0.0005078391,0.0002033429,0.00002630195,0.00577197,0.00002368313,0.0001164059,0.005626056],"study_design_scores_gemma":[0.000007201615,0.0001665829,0.9975068,0.000007266187,0.00002352965,0.001408105,0.0001531524,0.00005927241,0.0004657145,0.00003551029,0.0001635738,0.000003210813],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986832,0.0006139408,0.0001155441,0.00002981373,0.000008344972,0.000004326574,0.0002750791,0.000003599164,0.0002662377],"genre_scores_gemma":[0.9993555,0.0001830643,0.00007236327,0.00002826041,0.00001098852,0.000005076137,0.0002017233,0.000002335721,0.0001406904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001367635,"threshold_uncertainty_score":0.004575193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01454013988004813,"score_gpt":0.2761290646594973,"score_spread":0.2615889247794492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}