{"id":"W4409875572","doi":"10.21037/tcr-2024-2477","title":"Will phenotype help guide immunotherapy in prostate cancer?","year":2025,"lang":"en","type":"letter","venue":"Translational Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital; Université du Québec en Outaouais","funders":"","keywords":"Immunotherapy; Prostate cancer; Cancer; Medicine; Prostate; Phenotype; Oncology; Cancer research; Internal medicine; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001154492,0.0004374829,0.0007163181,0.001112213,0.0001936531,0.00007833335,0.0004409331,0.0006361228,0.005057863],"category_scores_gemma":[0.00002414921,0.0004017833,0.0002983932,0.001615986,0.0003948088,0.000203514,0.00003203686,0.003639464,0.00002367485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001334039,"about_ca_system_score_gemma":0.005627579,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02210114,"about_ca_topic_score_gemma":0.002584578,"domain_scores_codex":[0.9949287,0.0003375166,0.0007914157,0.0008500505,0.00206068,0.001031698],"domain_scores_gemma":[0.9981386,0.0003926155,0.0001096495,0.0005768757,0.0007040827,0.00007817163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006580527,0.00009408261,0.002139067,0.0009023104,0.0005749085,0.0002432037,0.0005919062,0.00004648798,0.003418219,0.00005011154,0.8895151,0.09584405],"study_design_scores_gemma":[0.005015658,0.0001690942,0.006076471,0.002014194,0.00003437645,0.000007606375,0.0000235332,0.000058127,0.0004884449,0.0006601287,0.9850827,0.0003696924],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001315882,0.0684771,0.00002540368,0.9188521,0.0006527228,0.002243868,0.0007781662,0.00006810684,0.007586664],"genre_scores_gemma":[0.004967728,0.1125483,0.0005206145,0.7249579,0.008777104,0.004318837,0.002133467,0.0003076353,0.1414684],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1938942,"threshold_uncertainty_score":0.9998434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06685955315953036,"score_gpt":0.4231772309204071,"score_spread":0.3563176777608767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}