{"id":"W4409898876","doi":"10.1093/rheumatology/keaf142.152","title":"P112 Cytokine driven disease and epigenetic heterogeneity in rheumatoid arthritis","year":2025,"lang":"en","type":"article","venue":"Lara D. Veeken","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Gilead Sciences","keywords":"Rheumatoid arthritis; Epigenetics; Cytokine; Disease; Medicine; Immunology; Biology; Internal medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002169789,0.0002304215,0.0002483596,0.0003452323,0.0001377559,0.0004190876,0.000180814,0.0003191716,0.002857685],"category_scores_gemma":[0.0002367758,0.0001817322,0.0002150043,0.0002488033,0.0003482309,0.00017007,0.0002980062,0.0005173815,0.0007460703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001310233,"about_ca_system_score_gemma":0.00009601137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000174836,"about_ca_topic_score_gemma":0.0003159236,"domain_scores_codex":[0.9997339,0.00002408604,0.00001541432,0.00011622,0.00007202892,0.00003840963],"domain_scores_gemma":[0.9997916,0.00003708861,0.00009120462,0.00002668347,0.00002393424,0.00002960486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001968099,0.00001356602,0.008932609,0.00008949202,0.00002401759,0.0001954827,0.00004363157,0.000151194,0.9845195,0.0001942825,0.0001611967,0.005478134],"study_design_scores_gemma":[0.00008403783,0.0009730042,0.6543413,0.00008842031,0.0001299749,0.007561608,0.0003634399,0.003972817,0.3144534,0.002777845,0.0151972,0.00005699574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801028,0.004513228,0.008953649,0.0002035914,0.00006038364,0.00003809547,0.002189961,0.0002482657,0.003689987],"genre_scores_gemma":[0.9950439,0.0005653986,0.001646427,0.0001222125,0.0000308421,0.00003523317,0.0007867957,0.00003541002,0.001733867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002857685,"threshold_uncertainty_score":0.009559929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01460882136787683,"score_gpt":0.2766611801316445,"score_spread":0.2620523587637677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}