{"id":"W4409908090","doi":"10.1182/blood.2025029042","title":"Counterpoint: the design and interpretation of blood transfusion randomized clinical trials","year":2025,"lang":"en","type":"review","venue":"Blood","topic":"Blood transfusion and management","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bruyère; University of Ottawa","funders":"","keywords":"Counterpoint; Medicine; Blood transfusion; Interpretation (philosophy); Randomized controlled trial; Intensive care medicine; Internal medicine; Computer science; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.3138245,0.002714348,0.01070154,0.00359926,0.001060642,0.008656183,0.005422917,0.01062938,0.00736019],"category_scores_gemma":[0.5273858,0.001491524,0.005445599,0.004559084,0.006569846,0.007178489,0.00307765,0.00995629,0.001429576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004795381,"about_ca_system_score_gemma":0.008098191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001644276,"about_ca_topic_score_gemma":0.00131583,"domain_scores_codex":[0.5308877,0.4045543,0.03340008,0.01244222,0.01791622,0.0007994989],"domain_scores_gemma":[0.3841096,0.5626929,0.02346287,0.016755,0.0120685,0.0009110318],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.009894319,0.0001802337,0.002497689,0.2526945,0.03192925,0.0002981794,0.001799093,0.002886045,0.000768055,0.1747913,0.08767924,0.4345821],"study_design_scores_gemma":[0.02034402,0.001679098,0.003140596,0.2929673,0.03428515,0.0006605441,0.000725026,0.009779689,0.001360361,0.3473043,0.2873326,0.0004213506],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.002761252,0.7445541,0.07509282,0.1252963,0.03953401,0.006365289,0.001292705,0.0004121513,0.004691414],"genre_scores_gemma":[0.1558939,0.2734428,0.2545405,0.2416954,0.03427324,0.03422366,0.001129016,0.0005239654,0.004277574],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.6861755,"threshold_uncertainty_score":0.8461766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09430663565613648,"score_gpt":0.4234981704247062,"score_spread":0.3291915347685698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}