{"id":"W4409922637","doi":"10.1080/17474086.2025.2500607","title":"Revolutionizing hypertension treatment: aprocitentan’s dual action against resistant hypertension","year":2025,"lang":"en","type":"editorial","venue":"Expert Review of Hematology","topic":"Blood Pressure and Hypertension Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Impact","funders":"","keywords":"Medicine; Resistant hypertension; Internal medicine; Cardiology; Intensive care medicine; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003904948,0.0008154174,0.005111019,0.000397266,0.0002922945,0.00001189815,0.0001783637,0.001267777,0.00007182476],"category_scores_gemma":[0.002041786,0.0005831038,0.0008866544,0.0004243357,0.000224439,0.00009214491,0.0002170912,0.000720065,0.00005073196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002117552,"about_ca_system_score_gemma":0.000883791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001727979,"about_ca_topic_score_gemma":0.00003805911,"domain_scores_codex":[0.9954892,0.0003140595,0.001642916,0.001080818,0.0009172105,0.0005557585],"domain_scores_gemma":[0.9950687,0.0009955529,0.000812219,0.001203473,0.001749845,0.0001702647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003926149,0.000454284,0.000007898846,0.01940007,0.001162464,0.0007094954,0.00005863054,2.769774e-8,0.003660222,0.00005384228,0.9667881,0.007312427],"study_design_scores_gemma":[0.001824036,0.0005629673,0.000008922246,0.05687487,0.003395174,0.0005555743,0.000151998,0.000007611629,0.001758727,0.00001538269,0.9344441,0.0004005878],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009376974,0.7579256,0.000009005363,0.003994289,0.2350543,0.001132479,0.00006716164,0.0001336027,0.001589785],"genre_scores_gemma":[0.0002682399,0.8590122,0.001149423,0.005547327,0.1300305,0.0002311829,0.00118197,0.00008297656,0.002496183],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1050238,"threshold_uncertainty_score":0.999662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04366818383536949,"score_gpt":0.3392756055108664,"score_spread":0.2956074216754969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}