{"id":"W4409949334","doi":"10.3390/cancers17091493","title":"Targeting c-MET Alterations in Cancer: A Review of Genetic Drivers and Therapeutic Implications","year":2025,"lang":"en","type":"review","venue":"Cancers","topic":"Liver physiology and pathology","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; National Institutes of Health","keywords":"Cancer; Medicine; Bioinformatics; Computational biology; Biology; Cancer research; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000450676,0.0006143083,0.0009324161,0.001932241,0.0001793358,0.0006152563,0.0006356548,0.0007155386,0.00287733],"category_scores_gemma":[0.000771406,0.0002091268,0.0004737945,0.001696222,0.0002545155,0.0008523222,0.0004704646,0.001175615,0.001262733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004770085,"about_ca_system_score_gemma":0.0008192534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006604327,"about_ca_topic_score_gemma":0.001244802,"domain_scores_codex":[0.9998631,0.00002446552,0.00002496753,0.00002600584,0.00004701277,0.0000144559],"domain_scores_gemma":[0.9997177,0.0001411952,0.00004118839,0.000006827693,0.00006835175,0.00002468716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008002073,0.00005045054,0.0001486395,0.02464113,0.0001085348,0.0002128141,0.00005453652,0.0003784257,0.002244542,0.002417515,0.03173269,0.9379306],"study_design_scores_gemma":[0.00001546472,0.000134551,0.0006288587,0.005210305,0.0001831123,0.001541986,0.00004821549,0.00007537321,0.00065061,0.001225969,0.9902673,0.00001820494],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001159135,0.9987709,0.0001047629,0.0002695398,0.0001376732,0.000004260204,0.00002812092,0.000007746878,0.0005609888],"genre_scores_gemma":[0.0004709199,0.9988838,0.000135261,0.0001490106,0.00008245739,0.000005499138,0.00003299225,0.000001355893,0.0002386958],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00287733,"threshold_uncertainty_score":0.009625614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04996538084609223,"score_gpt":0.3882128149084688,"score_spread":0.3382474340623766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}