{"id":"W4409952715","doi":"10.1038/s41467-025-58196-5","title":"Structural insights into terminal arabinosylation of mycobacterial cell wall arabinan","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; Fundação para a Ciência e a Tecnologia; Biotechnology and Biological Sciences Research Council; Horizon 2020 Framework Programme; U.S. Department of Health and Human Services; National Institutes of Health; Canadian Glycomics Network; National Institute of Allergy and Infectious Diseases; Medical Research Council; University of Warwick; Wellcome Trust; Engineering and Physical Sciences Research Council; Academia Sinica","keywords":"Lipoarabinomannan; Periplasmic space; Cell envelope; Arabinogalactan; Mycobacterium tuberculosis; Transmembrane domain; Transmembrane protein; Cell wall; Chemistry; Structural biology; Biochemistry; Biology; Membrane; Tuberculosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008235215,0.0003698938,0.000167929,0.0001077019,0.0003366903,0.0003204412,0.0003662592,0.0003333951,0.0009726728],"category_scores_gemma":[0.0001752045,0.0001915765,0.0001450688,0.0001526989,0.0003052456,0.0004465956,0.0001939339,0.0006590312,0.0001548926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003647237,"about_ca_system_score_gemma":0.0002871934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002923993,"about_ca_topic_score_gemma":0.002333649,"domain_scores_codex":[0.9999781,0.000003039828,7.898889e-7,0.00000450977,0.000007336364,0.000006218393],"domain_scores_gemma":[0.9999678,0.00000972707,0.000006802711,0.000002288106,0.000003472649,0.000009949388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007665507,0.0002015304,0.006354587,0.000412892,0.00005848946,0.001928964,0.0005522635,0.04344641,0.9249724,0.00791127,0.0007344094,0.01266022],"study_design_scores_gemma":[0.0004127941,0.000975211,0.05781839,0.0002107612,0.000180324,0.00235294,0.001392329,0.5656383,0.337402,0.01385633,0.01965475,0.0001058494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931544,0.001507669,0.00294163,0.0003137906,0.00001639218,0.000006656422,0.00007317418,0.0000855754,0.001900778],"genre_scores_gemma":[0.9959795,0.001532908,0.001910567,0.00005440181,0.000006386264,0.000005715183,0.0001736911,0.00001355313,0.0003232388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002923993,"threshold_uncertainty_score":0.005813897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009853016768612267,"score_gpt":0.3045625833899662,"score_spread":0.2947095666213539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}