{"id":"W4410022322","doi":"10.1016/j.mucimm.2025.04.008","title":"Anti-ST2 antibody reduces airway hyperresponsiveness mediated by monocyte-derived macrophages during influenza A infection","year":2025,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Immunology; Monocyte; Antibody; Medicine; Airway; Airway hyperresponsiveness; Virology; Immunity; Biology; Immune system; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001665348,0.0003075096,0.0002350386,0.0001655105,0.0001192082,0.0001669021,0.000136302,0.0002641975,0.0008785433],"category_scores_gemma":[0.00009488747,0.000100599,0.0001583862,0.00006255157,0.0001669211,0.0001198157,0.0001398819,0.0006894627,0.0001916616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001317253,"about_ca_system_score_gemma":0.0002046273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004813686,"about_ca_topic_score_gemma":0.001312505,"domain_scores_codex":[0.9998156,0.00004437593,0.00001316672,0.00001549687,0.00004029162,0.00007117182],"domain_scores_gemma":[0.9999104,0.000009295062,0.00002000868,0.000005840993,0.00001136585,0.00004314013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005006946,0.0001512394,0.0002880107,0.0000272315,0.000006177519,0.00002895418,0.00001359172,0.00003543699,0.9977679,0.00002758849,0.00005708792,0.00109595],"study_design_scores_gemma":[0.0001452754,0.00579375,0.02892816,0.00001922719,0.00004675379,0.0002369834,0.000088642,0.001541474,0.9609217,0.00005256685,0.002218312,0.000007180807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980701,0.000754757,0.000412555,0.00007056798,0.00002773999,0.00001742778,0.00006775192,0.00003110254,0.0005480108],"genre_scores_gemma":[0.9973493,0.0004064818,0.000494883,0.00008165247,0.00001674632,0.00003049521,0.0001500364,0.000006342726,0.00146419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008785433,"threshold_uncertainty_score":0.002939045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0100030079740676,"score_gpt":0.2722944659827381,"score_spread":0.2622914580086705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}