{"id":"W4410028092","doi":"10.2196/64360","title":"Optimizing a Personalized Health Approach for Virtually Treating High-Risk Caregivers of Children With Neurogenetic Conditions (Project WellCAST): Protocol for a Randomized Controlled Trial","year":2025,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Angelman Syndrome Foundation","keywords":"Preprint; Protocol (science); Randomized controlled trial; Medicine; Alternative medicine; Psychology; Gerontology; Computer science; World Wide Web","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03320231,0.007051485,0.01161444,0.003095602,0.004256656,0.005616621,0.0038149,0.008139913,0.103318],"category_scores_gemma":[0.03288442,0.003992743,0.006497525,0.003597263,0.003956954,0.004526201,0.003034471,0.01044579,0.01568381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005997353,"about_ca_system_score_gemma":0.01729989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003986071,"about_ca_topic_score_gemma":0.006216934,"domain_scores_codex":[0.9786583,0.01234622,0.002342118,0.002073528,0.00201858,0.002561228],"domain_scores_gemma":[0.9865921,0.004308593,0.002520018,0.00194769,0.002712269,0.00191932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8914332,0.02289713,0.000678267,0.01992646,0.002446067,0.0002248199,0.0005272469,0.002338205,0.001452078,0.004868531,0.01722744,0.03598064],"study_design_scores_gemma":[0.9512947,0.02093692,0.0008989106,0.002401322,0.0008219717,0.00003222916,0.0001330697,0.001440576,0.0004917147,0.002417404,0.01904607,0.00008512423],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.0009274452,0.0001311545,0.0006522806,0.0001002079,0.0001983612,0.9970254,0.0005480165,0.00005792267,0.0003592674],"genre_scores_gemma":[0.0007528764,0.00005346952,0.0009387514,0.00006612725,0.00002461124,0.9979398,0.00004764339,0.000003009269,0.0001737945],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.103318,"threshold_uncertainty_score":0.345633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05141794599855559,"score_gpt":0.4516682857679383,"score_spread":0.4002503397693827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}