{"id":"W4410050974","doi":"10.1093/jat/bkaf036","title":"From promise to practice: why HRMS has yet to fully revolutionize forensic toxicology","year":2025,"lang":"en","type":"article","venue":"Journal of Analytical Toxicology","topic":"Occupational and Professional Licensing Regulation","field":"Economics, Econometrics and Finance","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Office of the Chief Medical Examiner","funders":"","keywords":"Forensic toxicology; Forensic science; Good laboratory practice; Clinical toxicology; Toxicology; Medicine; Biology; Chemistry; Chromatography; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009426035,0.0001529061,0.0006296132,0.0006044692,0.0001490114,0.00006743955,0.0002591856,0.0002556079,0.0006132415],"category_scores_gemma":[0.004238586,0.0001467902,0.0001805923,0.0006280377,0.00009391097,0.0002460702,0.0001162597,0.0003387956,0.0003607262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003513517,"about_ca_system_score_gemma":0.0002328251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004497064,"about_ca_topic_score_gemma":0.00003977458,"domain_scores_codex":[0.9980194,0.00009690695,0.001156238,0.0003227341,0.000102114,0.0003026135],"domain_scores_gemma":[0.9978526,0.0007511562,0.0005161557,0.0002173818,0.0004118851,0.0002507941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002635867,0.0008007721,0.0136675,0.00002801275,0.0005680168,0.00007042616,0.0004714544,0.001687003,0.00163112,0.4454955,0.5270867,0.00585765],"study_design_scores_gemma":[0.001104127,0.001021209,0.07540823,0.00009475569,0.000087092,0.00004266328,0.000106792,0.002429456,0.0002625864,0.204001,0.7152042,0.0002378941],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5814266,0.0007423287,0.05051187,0.3450719,0.005743503,0.0005632332,0.0001227689,0.00002722448,0.0157906],"genre_scores_gemma":[0.937991,0.00001985836,0.03107626,0.02472107,0.0008499307,0.00001023598,0.00001414537,0.00001815926,0.005299385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3565643,"threshold_uncertainty_score":0.6714564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04467090552009678,"score_gpt":0.3203994526883464,"score_spread":0.2757285471682496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}