{"id":"W4410053822","doi":"10.1016/j.ajo.2025.04.034","title":"Natural History of Microperimetry and Optical Coherence Tomography in USH2A-Retinopathy: A Structure-Function Association Study","year":2025,"lang":"en","type":"article","venue":"American Journal of Ophthalmology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Eye Institute; Foundation for the National Institutes of Health; Oregon Health and Science University; National Institutes of Health; Foundation Fighting Blindness; Research to Prevent Blindness","keywords":"Microperimetry; Optical coherence tomography; Tomography; Ophthalmology; Medicine; Association (psychology); Optometry; Psychology; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001019675,0.0005900906,0.0005400847,0.001879491,0.001378076,0.0009854923,0.0009686984,0.001322682,0.003230701],"category_scores_gemma":[0.003122782,0.0006601328,0.001160442,0.001716549,0.0009417811,0.001263944,0.0008540175,0.001379214,0.0005124789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005163025,"about_ca_system_score_gemma":0.000611465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005091198,"about_ca_topic_score_gemma":0.003475701,"domain_scores_codex":[0.9989625,0.0002931489,0.00009567903,0.0003408673,0.0001299468,0.0001779305],"domain_scores_gemma":[0.9966109,0.0008586018,0.00104137,0.0004453849,0.0003619207,0.0006818871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003871282,0.0001974748,0.9959363,0.000005774993,0.0001087581,0.0007957753,0.0001675512,0.00004123191,0.0008590125,0.0001075759,0.0001167899,0.001276589],"study_design_scores_gemma":[0.00001221884,0.0002008684,0.9969128,0.00000412237,0.00006103066,0.001843583,0.000246543,0.0002855673,0.0001168299,0.0001283461,0.0001750905,0.00001300464],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985951,0.0003037561,0.000152577,0.0001133126,0.000008715994,0.000008109074,0.0002356652,0.000008450666,0.0005744161],"genre_scores_gemma":[0.9990791,0.00009261681,0.00007601954,0.0000383321,0.0000210176,0.000006962742,0.0002053812,0.000007213682,0.0004733402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005091198,"threshold_uncertainty_score":0.01080775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004573606587725002,"score_gpt":0.2428737026874959,"score_spread":0.2383000960997709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}