{"id":"W4410075696","doi":"10.1021/acs.analchem.5c00505","title":"Single-Tube Multiplex Detection of High-Risk HPV Subtypes Utilizing Lanthanide Nanoprobes","year":2025,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Fundamental Research Funds for the Central Universities; Department of Science and Technology of Sichuan Province; National Natural Science Foundation of China","keywords":"Chemistry; Multiplex; Lanthanide; Tube (container); Nanotechnology; Chromatography; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008317656,0.0009137858,0.0006083104,0.0007960538,0.0002435257,0.0004593208,0.0007137287,0.0009564939,0.0007911194],"category_scores_gemma":[0.0007272436,0.0005107053,0.0003309579,0.0002391837,0.0003831226,0.0006519992,0.0006941785,0.0004682883,0.0005118169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003273177,"about_ca_system_score_gemma":0.0002762114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003353303,"about_ca_topic_score_gemma":0.0009217167,"domain_scores_codex":[0.9992392,0.0001194024,0.00005010077,0.0003121959,0.0002063782,0.000072688],"domain_scores_gemma":[0.9996313,0.0001139354,0.00008516524,0.00004045775,0.00009520207,0.00003389346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004145064,0.00001530295,0.000234428,0.00008989847,0.00001611385,0.00006514072,0.00003699255,0.0001326237,0.9947231,0.0001427089,0.00008625192,0.00441598],"study_design_scores_gemma":[0.000004691777,0.00009233372,0.0003984724,0.000007135939,0.00001495035,0.0001565247,0.00001961948,0.004066209,0.9942089,0.00007700019,0.0009392431,0.00001487408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.693765,0.005604842,0.2927679,0.0003369383,0.0002552375,0.0003794647,0.0007877653,0.00254719,0.003555587],"genre_scores_gemma":[0.7340484,0.002475027,0.2573582,0.0002377761,0.00004412182,0.0003954276,0.0003619516,0.0001121779,0.004966997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009564939,"threshold_uncertainty_score":0.004398882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008686992287189312,"score_gpt":0.2560931973303793,"score_spread":0.24740620504319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}