{"id":"W4410079202","doi":"10.1093/braincomms/fcaf168","title":"Safety and efficacy of bilateral staged focused ultrasound thalamotomy in refractory essential tremor","year":2025,"lang":"en","type":"article","venue":"Brain Communications","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Thalamotomy; Essential tremor; Focused ultrasound; Refractory (planetary science); Medicine; Physical medicine and rehabilitation; Ultrasound; Radiology; Deep brain stimulation; Materials science; Parkinson's disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002774174,0.0002321689,0.0007084186,0.0001234913,0.00009139729,0.0001305946,0.0001751826,0.0002540396,0.0008954894],"category_scores_gemma":[0.0005942692,0.00007099015,0.0003260958,0.0001013785,0.0001284602,0.000174774,0.0001115038,0.0004116216,0.0001120019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001662003,"about_ca_system_score_gemma":0.0001744087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003322354,"about_ca_topic_score_gemma":0.001200817,"domain_scores_codex":[0.9998628,0.00004415841,0.00001574904,0.00002337893,0.00003852263,0.00001546763],"domain_scores_gemma":[0.9997814,0.00006139499,0.00007402013,0.00002060141,0.00002064456,0.0000418961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1321731,0.009889903,0.02009043,0.001492154,0.001037359,0.001070605,0.000268723,0.002140712,0.1959422,0.00012612,0.001163859,0.6346049],"study_design_scores_gemma":[0.04700435,0.6477649,0.2661749,0.0001778684,0.001170234,0.003065242,0.0001759204,0.004905992,0.02484093,0.0001930962,0.004453706,0.00007287066],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969578,0.002126829,0.000202689,0.00004586347,0.000013863,0.00006310873,0.00007501527,0.00001817254,0.0004967041],"genre_scores_gemma":[0.9983998,0.0008503997,0.0001726018,0.00006898743,0.0000303886,0.00005461041,0.0001322506,0.000002074255,0.0002890133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008954894,"threshold_uncertainty_score":0.002995729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02220155843804433,"score_gpt":0.3179594393725425,"score_spread":0.2957578809344982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}