{"id":"W4410082681","doi":"10.20944/preprints202505.0011.v1","title":"Nanobodies Open New Avenues in Cancer Treatment: Beyond a Laboratory Bench","year":2025,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Bench to bedside; Cancer; Nanotechnology; Medicine; Computer science; Computational biology; Medical physics; Biology; Internal medicine; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004258904,0.0005763659,0.001672264,0.0009276289,0.000988855,0.005195021,0.001071742,0.0038675,0.009044103],"category_scores_gemma":[0.002758066,0.0003736407,0.0008157336,0.0007204641,0.005666315,0.01113242,0.002849855,0.00895873,0.003983168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001442569,"about_ca_system_score_gemma":0.001812712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003016988,"about_ca_topic_score_gemma":0.0003476093,"domain_scores_codex":[0.9982657,0.0005764408,0.00005937687,0.000248844,0.000677213,0.0001724016],"domain_scores_gemma":[0.9975101,0.001360893,0.000110715,0.0003073291,0.0003779084,0.0003330476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007096931,0.0004264954,0.001045293,0.003641222,0.0001831757,0.0006409318,0.001179016,0.001440501,0.04599427,0.3747666,0.1060529,0.4639199],"study_design_scores_gemma":[0.00007556078,0.0003899912,0.0004508166,0.0007198934,0.00004352316,0.0006993501,0.0004683508,0.0006102417,0.01038797,0.1575304,0.8285706,0.00005329137],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.008461392,0.7605308,0.03899544,0.1514848,0.0080044,0.0001049443,0.000297229,0.0006884619,0.03143246],"genre_scores_gemma":[0.1433142,0.7061124,0.03780435,0.06589746,0.01861113,0.0003520488,0.0005198391,0.0006133678,0.02677534],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.009044103,"threshold_uncertainty_score":0.03025556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2065360379907643,"score_gpt":0.4616943656707261,"score_spread":0.2551583276799618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}