{"id":"W4410116091","doi":"10.1016/b978-0-443-19088-9.00010-x","title":"The dependence of basal forebrain cholinergic neurons on NGF: The case in Alzheimer pathology","year":2025,"lang":"en","type":"review","venue":"Handbook of clinical neurology","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Basal forebrain; Cholinergic neuron; Cholinergic; Neuroscience; Pathology; Tau pathology; Basal (medicine); Psychology; Medicine; Alzheimer's disease; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000699029,0.00114132,0.001620172,0.002385634,0.0002804983,0.001491892,0.001229365,0.00206206,0.002962757],"category_scores_gemma":[0.0006333713,0.0003215622,0.0003182206,0.002613014,0.001146581,0.002022541,0.000968278,0.002332631,0.002429693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000933268,"about_ca_system_score_gemma":0.001344284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001885743,"about_ca_topic_score_gemma":0.004652115,"domain_scores_codex":[0.9998227,0.00002228762,0.00002654448,0.00003431797,0.00007642298,0.00001782419],"domain_scores_gemma":[0.9997085,0.0001481898,0.00004262506,0.00001097145,0.00005986029,0.00002979238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000801592,0.00004683897,0.0001698813,0.01140614,0.00004273253,0.000516845,0.00009020494,0.0001998698,0.002032264,0.005634289,0.05968022,0.9201006],"study_design_scores_gemma":[0.00001383414,0.00005133691,0.0008966433,0.004726578,0.00005581653,0.002561362,0.0001145393,0.00006357965,0.0002605955,0.004786966,0.9864442,0.00002456493],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004516944,0.9988431,0.00007371681,0.0001765461,0.0002035006,0.000001403944,0.000008285361,0.00000454476,0.0006436658],"genre_scores_gemma":[0.0003374156,0.9982096,0.0001966614,0.0002552978,0.0002815118,0.000003561512,0.00001320553,0.000001252693,0.0007014702],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002962757,"threshold_uncertainty_score":0.009911418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1857332098395747,"score_gpt":0.4545676214034869,"score_spread":0.2688344115639122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}