{"id":"W4410141094","doi":"10.2139/ssrn.5242133","title":"Psilocybin Induces Sex- and Context-Specific Recruitment of the Stress Axis","year":2025,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Krembil Foundation; University of Toronto; Hotchkiss Brain Institute; University of Calgary","funders":"","keywords":"Psilocybin; Context (archaeology); Psychology; Hallucinogen; Psychiatry; Geography; Archaeology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00127954,0.0003316276,0.0005430601,0.0001549763,0.0002673926,0.00005296359,0.0006984874,0.0002971507,0.00004945566],"category_scores_gemma":[0.0000278968,0.00023069,0.0002465179,0.00013766,0.0001957386,0.00002409551,0.0005863623,0.003878429,0.000004828222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003784011,"about_ca_system_score_gemma":0.001351562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003731044,"about_ca_topic_score_gemma":0.0014546,"domain_scores_codex":[0.9969987,0.0003193617,0.0005865619,0.0004542948,0.0002842727,0.00135679],"domain_scores_gemma":[0.9985539,0.0001300512,0.0005309926,0.0005781065,0.0001512965,0.0000557099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001880135,0.000372951,0.006684994,0.00007642229,0.003273358,0.000004013325,0.00641589,0.00001663459,0.0001006555,0.6892394,0.003923712,0.289704],"study_design_scores_gemma":[0.003395913,0.000592898,0.02120387,0.001053278,0.0004763632,0.0002262437,0.05289606,0.000009164235,0.0005580461,0.8317114,0.08695827,0.0009184728],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7300882,0.2419026,0.0003270922,0.003893153,0.004046989,0.0009367486,0.0001506593,0.00002583997,0.01862866],"genre_scores_gemma":[0.9522189,0.03750567,0.00001101719,0.0001252239,0.0003056091,0.00007923013,0.00000423027,0.00001906972,0.009731006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2887855,"threshold_uncertainty_score":0.9984196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06528691345279922,"score_gpt":0.3482242796044706,"score_spread":0.2829373661516713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}