{"id":"W4410171439","doi":"10.1007/s12311-025-01849-4","title":"Selection of Clinical Outcome Assessments for Trial Readiness in ARSACS – 2-year Progression and Responsiveness to Change Part 2: Mobility, Balance, and Lower Limb Coordination","year":2025,"lang":"en","type":"article","venue":"The Cerebellum","topic":"Cerebral Palsy and Movement Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Chicoutimi; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke; Centres Intégré Universitaires de Santé et de Services Sociaux; Centre for Interdisciplinary Research in Rehabilitation; Montreal Neurological Institute and Hospital; Cégep de Jonquière; Université Laval; McGill University; Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean","funders":"Canadian Institutes of Health Research","keywords":"Balance (ability); Outcome (game theory); Physical medicine and rehabilitation; Selection (genetic algorithm); Neurology; Medicine; Physical therapy; Psychology; Psychiatry; Computer science; Economics; Microeconomics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02018418,0.001406527,0.003295132,0.002469865,0.001713462,0.001940203,0.001024749,0.001842848,0.003784751],"category_scores_gemma":[0.02619205,0.000350723,0.004714022,0.001358184,0.00100932,0.00218354,0.001803814,0.0014772,0.001581258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001714778,"about_ca_system_score_gemma":0.004662907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001829306,"about_ca_topic_score_gemma":0.005233293,"domain_scores_codex":[0.9900848,0.004898751,0.001695353,0.0009044019,0.00119755,0.001219294],"domain_scores_gemma":[0.9863258,0.003640003,0.003490949,0.001039941,0.003830607,0.00167271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1622683,0.005603966,0.6661885,0.001521016,0.002619779,0.0004910065,0.001918606,0.003430626,0.006279367,0.001669996,0.008415426,0.1395933],"study_design_scores_gemma":[0.01332222,0.04577855,0.9145105,0.0007975843,0.001701111,0.0003581037,0.001056259,0.007036761,0.004331782,0.002541742,0.008310868,0.000254528],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.964434,0.001480785,0.004659254,0.0007354389,0.0002867829,0.01858218,0.002281325,0.0001605145,0.007379808],"genre_scores_gemma":[0.9701182,0.0002166791,0.004800358,0.0003201305,0.00007070781,0.02073421,0.002296161,0.00005244105,0.001391138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02018418,"threshold_uncertainty_score":0.1067454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08005287065148518,"score_gpt":0.4412644428190786,"score_spread":0.3612115721675934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}