{"id":"W4410186454","doi":"10.1080/14737175.2025.2500757","title":"Pharmacological therapies for early and long-term recovery in disorders of consciousness: current knowledge and promising avenues","year":2025,"lang":"en","type":"review","venue":"Expert Review of Neurotherapeutics","topic":"Traumatic Brain Injury Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Koning Boudewijnstichting; Université de Montréal; Fundação Bial; Mind Science Foundation; Fonds De La Recherche Scientifique - FNRS; Fonds Léon Fredericq; Canadian Institute for Advanced Research","keywords":"Term (time); Psychology; Neuroscience; Persistent vegetative state; Medicine; Current (fluid); Consciousness; Psychotherapist; Intensive care medicine; Minimally conscious state; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000565853,0.0003677212,0.002608883,0.0002756729,0.0000321041,0.00001398255,0.000189783,0.0001535734,0.00002198387],"category_scores_gemma":[0.0002604994,0.0002634944,0.0003489658,0.0003181575,0.0003546757,0.00004312355,0.00009070656,0.0003803565,5.07018e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004108945,"about_ca_system_score_gemma":0.000368871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001611697,"about_ca_topic_score_gemma":0.000002905813,"domain_scores_codex":[0.9976213,0.0004582817,0.001058863,0.0004129003,0.0001971434,0.0002515089],"domain_scores_gemma":[0.997577,0.00156113,0.0003814677,0.0002963794,0.0001114308,0.00007257572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003984614,0.0002040954,0.0002089663,0.3174686,0.0001529022,0.000001418079,0.0001795966,1.267612e-9,0.00001420585,0.00001325368,0.00007269012,0.6816444],"study_design_scores_gemma":[0.001015928,0.0006393547,0.0006513077,0.4085865,0.0007575847,0.00002223721,0.000006486065,0.00000264936,0.00000998296,0.00005756536,0.5880309,0.0002194002],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004261746,0.9931747,0.00004359795,0.0002300351,0.0001986895,0.005819091,0.0000453901,0.00001434149,0.00004793029],"genre_scores_gemma":[0.00004477375,0.9986693,0.0003153258,0.0001829396,0.00006588469,0.0006094815,0.00001379878,0.0000465275,0.00005196688],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6814251,"threshold_uncertainty_score":0.9999817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1392025084151167,"score_gpt":0.4852754470721399,"score_spread":0.3460729386570232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}