{"id":"W4410196424","doi":"10.1007/s13659-025-00508-9","title":"New sesquiterpenoids with anti-inflammatory effects from phytopathogenic fungus Bipolaris sorokiniana 11134","year":2025,"lang":"en","type":"article","venue":"Natural Products and Bioprospecting","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Key Research and Development Program of China; State Key Laboratory of Bioreactor Engineering; Higher Education Discipline Innovation Project; Shanghai Rising-Star Program; Science and Technology Commission of Shanghai Municipality; National Natural Science Foundation of China","keywords":"Bipolaris; In vitro; Antimicrobial; Gliotoxin; Anti-inflammatory; Fungus; Bioorganic chemistry; Chemistry; Biology; Stereochemistry; Biochemistry; Microbiology; Botany; Pharmacology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002641374,0.0004456493,0.0006425354,0.0002177376,0.0003479874,0.0001715434,0.0001633135,0.00020852,0.00003631601],"category_scores_gemma":[0.0003995246,0.0002849961,0.0000948047,0.0008304971,0.0001194791,0.0002354811,0.0001557689,0.0007745954,0.00001484359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001004321,"about_ca_system_score_gemma":0.0001856606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004205656,"about_ca_topic_score_gemma":0.00004511476,"domain_scores_codex":[0.9976396,0.0000313749,0.000376813,0.001125619,0.000293557,0.0005330521],"domain_scores_gemma":[0.9987944,0.00008892499,0.0001720212,0.0005418395,0.0002523627,0.0001504691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002774863,0.0000533868,0.03419368,0.0005136609,0.0002121853,0.0001009212,0.0001474331,1.654409e-7,0.8892888,0.0001880788,0.001004047,0.07402012],"study_design_scores_gemma":[0.001593872,0.000235542,0.1960737,0.000795268,0.0003968222,0.0001315729,0.00006360663,0.00002279673,0.7938705,0.0002031579,0.006183284,0.0004298647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9641122,0.028241,0.0000129419,0.004991251,0.001022774,0.001016712,0.00001262063,0.0002303893,0.0003601791],"genre_scores_gemma":[0.9866727,0.000208069,0.00481628,0.0007087148,0.001615437,0.000001704919,0.00003001109,0.00003876783,0.005908304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.16188,"threshold_uncertainty_score":0.9999602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003422004776496324,"score_gpt":0.2127459101794215,"score_spread":0.2093239054029252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}