{"id":"W4410196424","doi":"10.1007/s13659-025-00508-9","title":"New sesquiterpenoids with anti-inflammatory effects from phytopathogenic fungus Bipolaris sorokiniana 11134","year":2025,"lang":"en","type":"article","venue":"Natural Products and Bioprospecting","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Key Research and Development Program of China; State Key Laboratory of Bioreactor Engineering; Higher Education Discipline Innovation Project; Shanghai Rising-Star Program; Science and Technology Commission of Shanghai Municipality; National Natural Science Foundation of China","keywords":"Bipolaris; In vitro; Antimicrobial; Gliotoxin; Anti-inflammatory; Fungus; Bioorganic chemistry; Chemistry; Biology; Stereochemistry; Biochemistry; Microbiology; Botany; Pharmacology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005719534,0.0005219814,0.0002480103,0.0004184695,0.0001142621,0.0001822724,0.0001138158,0.0001824477,0.0009808238],"category_scores_gemma":[0.00006315351,0.0001079845,0.0001822764,0.0002866458,0.00014284,0.0001779673,0.000172453,0.0002570545,0.0002808486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008303828,"about_ca_system_score_gemma":0.0002076375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004440173,"about_ca_topic_score_gemma":0.001118151,"domain_scores_codex":[0.9999714,0.000005226753,0.000003336786,0.000005866674,0.000008290316,0.000005781202],"domain_scores_gemma":[0.9999735,0.000003168868,0.000005864661,0.000002415627,0.000004691658,0.0000103655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001240353,0.00004112841,0.0002131744,0.0001875917,0.000008449055,0.000257054,0.00002520416,0.0001457204,0.9929844,0.0001001019,0.00005952161,0.005853576],"study_design_scores_gemma":[0.0002259643,0.002516879,0.0217698,0.00009935514,0.0001387754,0.00119778,0.0001938608,0.001016387,0.9519212,0.0003642282,0.02051781,0.00003794194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840519,0.006063758,0.003517793,0.0001217218,0.00003808779,0.0001528853,0.001252715,0.000083062,0.004718055],"genre_scores_gemma":[0.9845204,0.004848951,0.005228221,0.0001374762,0.00001665779,0.0000644821,0.001835782,0.00001922342,0.003328819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009808238,"threshold_uncertainty_score":0.003281176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003422004776496324,"score_gpt":0.2127459101794215,"score_spread":0.2093239054029252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}