{"id":"W4410207110","doi":"10.1152/japplphysiol.00038.2025","title":"Effect of aging, endurance training, and denervation on innate immune signaling in skeletal muscle","year":2025,"lang":"en","type":"article","venue":"Journal of Applied Physiology","topic":"Exercise and Physiological Responses","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitochondrial biogenesis; Skeletal muscle; Denervation; Endurance training; Inflammasome; Internal medicine; Mitochondrion; Endocrinology; Biology; Reactive oxygen species; Autophagy; Innate immune system; Apoptosis; Cell biology; Inflammation; Medicine; Immune system; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003334335,0.0003572204,0.0004118557,0.0001470865,0.000167919,0.0002395007,0.0001475719,0.0002535228,0.001308901],"category_scores_gemma":[0.0001394531,0.00007424271,0.0002972998,0.0001236136,0.0002864149,0.0003255432,0.0002714943,0.0003918441,0.0001127506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001373928,"about_ca_system_score_gemma":0.0002418797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005530257,"about_ca_topic_score_gemma":0.001683977,"domain_scores_codex":[0.999872,0.00002278434,0.00001849654,0.00003470444,0.00001547072,0.0000365218],"domain_scores_gemma":[0.9999053,0.00001716621,0.0000282291,0.00001326813,0.00001105579,0.00002488643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007828474,0.001066991,0.008761285,0.0008184348,0.0002025011,0.0002262314,0.0001773254,0.0002639229,0.9462099,0.0001609744,0.0001762431,0.03410768],"study_design_scores_gemma":[0.0003201613,0.04114328,0.5882508,0.000335574,0.0007232379,0.000896265,0.0009126585,0.001466082,0.3561635,0.0005157356,0.009227352,0.00004530964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878024,0.01064454,0.0005333262,0.0001280515,0.00009614293,0.00002319149,0.0001241146,0.000009307802,0.0006389931],"genre_scores_gemma":[0.9916795,0.005252547,0.0008054284,0.0002031246,0.00005923468,0.000065546,0.0002489779,0.000004064915,0.001681589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001308901,"threshold_uncertainty_score":0.004378676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01279558685761259,"score_gpt":0.2974552082320017,"score_spread":0.2846596213743891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}