{"id":"W4410208860","doi":"10.2139/ssrn.5179036","title":"Immunogenicity and Safety of Half and Full Doses of Heterologous and Homologous Covid-19 Vaccine Boosters after Priming with Chadox1-S in Adult Participants in Indonesia: A Single-Blinded Randomized Controlled Trial","year":2025,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Immunogenicity; Heterologous; Randomized controlled trial; Priming (agriculture); Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Virology; Medicine; Immunology; Biology; Internal medicine; Immune system; Genetics; Gene; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002537614,0.00192929,0.004316083,0.0003666077,0.0005918279,0.001180838,0.001123471,0.002361662,0.005668701],"category_scores_gemma":[0.002532077,0.001125318,0.002067187,0.0003973123,0.001761877,0.001378442,0.0004770815,0.003010786,0.001099251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001038231,"about_ca_system_score_gemma":0.001368342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008755198,"about_ca_topic_score_gemma":0.0008340037,"domain_scores_codex":[0.9984671,0.0006312735,0.0001505943,0.0003843032,0.0001382047,0.0002284914],"domain_scores_gemma":[0.9983709,0.0004440293,0.0004079987,0.0001840103,0.0001493409,0.0004436609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9768537,0.01262338,0.0007206848,0.0003466218,0.0004504729,0.00002026854,0.00007437117,0.0001330808,0.001818228,0.00003565528,0.0001347595,0.006788824],"study_design_scores_gemma":[0.6746739,0.3157074,0.005934152,0.00007727343,0.001188433,0.00002681421,0.00007184687,0.000477957,0.001210619,0.0001366709,0.0004606932,0.0000344166],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947829,0.001138554,0.0003288462,0.000122652,0.0002257736,0.002502328,0.0002915901,0.00003456464,0.0005727896],"genre_scores_gemma":[0.9927472,0.0007514885,0.000822545,0.0002926605,0.000211515,0.003586076,0.000305934,0.00001306751,0.001269461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005668701,"threshold_uncertainty_score":0.01896369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02487489749395189,"score_gpt":0.3203146716590839,"score_spread":0.295439774165132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}