{"id":"W4410212813","doi":"10.1242/jcs.263907","title":"A lipid in transit – the journey of cholesterol into the heart of mitochondrial research","year":2025,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Mitochondrion; Biology; Phosphatidylethanolamine; Cell biology; Cholesterol; Inner mitochondrial membrane; Organelle; Phospholipid; Biochemistry; Mitochondrial membrane transport protein; Mitophagy; Inner membrane; Membrane; Apoptosis; Phosphatidylcholine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002533483,0.00005395287,0.0001389288,0.000179973,0.0001075622,0.00001979954,0.0006439423,0.00006379745,0.00001462108],"category_scores_gemma":[0.0004005274,0.00002919325,0.00009104315,0.0006261399,0.0007559216,0.000008542499,0.00007991032,0.0002866765,9.567165e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001346132,"about_ca_system_score_gemma":0.0005333515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003110838,"about_ca_topic_score_gemma":0.0000929187,"domain_scores_codex":[0.9986826,0.0002829458,0.0003836104,0.0001217422,0.0003663576,0.0001627996],"domain_scores_gemma":[0.9990541,0.00009000549,0.0001552792,0.0002537708,0.0004056222,0.0000412215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001930012,0.00005020792,0.00059349,0.000009656624,0.000003694372,7.021569e-7,0.0006283895,0.0001305779,0.9957266,0.00007109577,0.002156382,0.00043613],"study_design_scores_gemma":[0.0006285718,0.0004930313,0.002759736,0.000041436,0.000007103518,0.00002431365,0.0005775996,0.00002607199,0.9614172,0.0002140162,0.03377857,0.00003234086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991717,0.0004406167,0.001327808,0.003326441,0.001034129,0.0001346851,7.740227e-7,4.269814e-7,0.002018061],"genre_scores_gemma":[0.9982577,0.0001582987,0.0005957225,0.0002460639,0.0002328517,0.000001776098,1.609035e-7,0.000002449492,0.0005050085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03430946,"threshold_uncertainty_score":0.2785225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02378778430858683,"score_gpt":0.3345562123198548,"score_spread":0.310768428011268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}