{"id":"W4410217424","doi":"10.1016/j.bone.2025.117517","title":"Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice","year":2025,"lang":"en","type":"article","venue":"Bone","topic":"Bone health and treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences","keywords":"Osteolysis; Breast cancer; Medicine; Oncology; Internal medicine; Cancer; Dentistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004624291,0.0001078635,0.0003518499,0.0001427156,0.00003506802,0.000004345751,0.00001651614,0.00006178881,0.000008137737],"category_scores_gemma":[0.00002914931,0.00008539999,0.00003108763,0.0001405173,0.00001397933,0.00001753748,0.00001735951,0.0001156564,0.000002553076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001066122,"about_ca_system_score_gemma":0.00006396214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002264486,"about_ca_topic_score_gemma":0.0007355438,"domain_scores_codex":[0.9993306,0.00003930711,0.0001766722,0.0001795146,0.0000970877,0.0001768412],"domain_scores_gemma":[0.9996282,0.00008660751,0.00005902948,0.0001186408,0.00001826916,0.00008926528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007173297,0.001781171,0.3938916,0.003532774,0.0003972852,0.0003722484,0.001022647,0.000006469209,0.3484121,0.0002661278,0.0002170191,0.2429272],"study_design_scores_gemma":[0.007234247,0.0002197492,0.9118042,0.00116511,0.0001476266,0.000008809387,0.00001267878,0.0003039794,0.07899303,0.00004191887,0.000004981082,0.00006367877],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978456,0.0003247815,0.000004609491,0.0009756304,0.0001169492,0.0004073477,0.000009123484,0.00001259171,0.0003033368],"genre_scores_gemma":[0.9990059,0.00006420885,0.00001840065,0.0003355432,0.00001734806,0.00003847743,0.000005218672,0.00000797866,0.0005069521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5179126,"threshold_uncertainty_score":0.348251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01206184309074902,"score_gpt":0.2873803110548428,"score_spread":0.2753184679640938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}