{"id":"W4410233069","doi":"10.1371/journal.pone.0322477","title":"Matching plasma and tissue miRNA expression analysis to detect viable ovarian germ cell tumors","year":2025,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Testicular diseases and treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Health Research","keywords":"Germ cell tumors; microRNA; Germ cell; Oncology; Biology; Pathology; Ovarian cancer; Medicine; Internal medicine; Andrology; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006291986,0.0002048951,0.0004155057,0.001042378,0.0002232741,0.0006396055,0.0002221629,0.0002755735,0.001533694],"category_scores_gemma":[0.001640178,0.0001370203,0.0001846873,0.0008344623,0.0002237705,0.0002293142,0.0001983805,0.0002942687,0.0004370146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003580828,"about_ca_system_score_gemma":0.0004420061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000655912,"about_ca_topic_score_gemma":0.0009805248,"domain_scores_codex":[0.9995296,0.000102517,0.0000617672,0.0001382734,0.0001248661,0.00004305746],"domain_scores_gemma":[0.9994111,0.0001517337,0.0002172312,0.0000555178,0.0001070954,0.00005731985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002260793,0.0001121507,0.8235981,0.0002552744,0.00009451895,0.0007393757,0.0002729941,0.0006381,0.1233983,0.0002758701,0.0008391763,0.04751538],"study_design_scores_gemma":[0.00007979757,0.001347027,0.8719499,0.00005784689,0.0001552809,0.006949923,0.0004072759,0.005019763,0.1061005,0.0004807438,0.007423439,0.00002851548],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845344,0.002994267,0.008573431,0.0001256404,0.00004690323,0.0001339361,0.001496977,0.0001365504,0.001957928],"genre_scores_gemma":[0.9911247,0.0004799747,0.006727609,0.00007327517,0.00001988605,0.00008565043,0.0008727783,0.000024149,0.0005918882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001533694,"threshold_uncertainty_score":0.005130708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01386541555689442,"score_gpt":0.2488173616498031,"score_spread":0.2349519460929087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}