{"id":"W4410237071","doi":"10.1016/j.ijrobp.2025.04.039","title":"PSMA MRI Guided prOstate SBRT (ARGOS)/Comprehensive, Longitudinal Evaluation of IMaging BiomarkErs Post Radiotherapy (CLIMBER) Phase I/II Trial","year":2025,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"St Joseph's Health Centre; St Joseph's Health Care; Health Sciences Centre; London Health Sciences Centre; Lawson Health Research Institute; Sunnybrook Health Science Centre; Western University","funders":"Ontario Institute for Cancer Research; Bayer; Astellas Pharma US","keywords":"SABR volatility model; Clinical endpoint; Medicine; Prostate; Nuclear medicine; Randomized controlled trial; Internal medicine; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001138877,0.001416534,0.001826552,0.0002572857,0.000424634,0.001016422,0.0006417139,0.0007842671,0.004461674],"category_scores_gemma":[0.0005387777,0.0003557044,0.00117239,0.0003071071,0.0008690713,0.0006232217,0.0004520971,0.001945184,0.001066789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009235554,"about_ca_system_score_gemma":0.001992546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0021425,"about_ca_topic_score_gemma":0.009065731,"domain_scores_codex":[0.9997261,0.0001094464,0.000007183412,0.00006842538,0.00002491568,0.00006391007],"domain_scores_gemma":[0.9995765,0.00003560101,0.0001028483,0.00003595,0.00002631812,0.0002227388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8073376,0.02055401,0.007807485,0.001262621,0.002440119,0.0001447369,0.000360592,0.004695368,0.02274968,0.001146446,0.01393234,0.117569],"study_design_scores_gemma":[0.6471666,0.3115951,0.02366955,0.0001785456,0.00142573,0.0002844802,0.0001738371,0.002289049,0.002802321,0.001491378,0.00885076,0.00007262631],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872298,0.003593515,0.0006735189,0.001110624,0.0002681964,0.001114333,0.001841164,0.0002634531,0.003905373],"genre_scores_gemma":[0.9709839,0.003405848,0.003383446,0.00253279,0.0002802099,0.00199719,0.004739904,0.0001259599,0.01255068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004461674,"threshold_uncertainty_score":0.01492578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04413005979093215,"score_gpt":0.4183323431117366,"score_spread":0.3742022833208044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}