{"id":"W4410267798","doi":"10.1177/25158414251321730","title":"Plain-language commentary: 2-year findings from the FIREFLEYE next study looking at how well aflibercept injected into affected eyes in babies with retinopathy of prematurity works and how safe it is compared with laser treatment","year":2025,"lang":"en","type":"editorial","venue":"Therapeutic Advances in Ophthalmology","topic":"Retinopathy of Prematurity Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bayer (Canada)","funders":"","keywords":"Aflibercept; Retinopathy of prematurity; Medicine; Ophthalmology; Pediatrics; Optometry; Surgery; Gestational age; Pregnancy; Bevacizumab; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004669608,0.00100432,0.002502811,0.000334462,0.0002250545,0.00007782597,0.0005055675,0.0006552897,0.00008377001],"category_scores_gemma":[0.0002247339,0.0006355383,0.0001079382,0.0004992108,0.001085802,0.0002468367,0.0004022997,0.001419871,0.000001505022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007148577,"about_ca_system_score_gemma":0.0001542569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009572469,"about_ca_topic_score_gemma":0.005944682,"domain_scores_codex":[0.9956759,0.001116481,0.0005659302,0.001204383,0.000787277,0.0006499893],"domain_scores_gemma":[0.9937475,0.004497247,0.0005867097,0.0008984845,0.0001827106,0.00008733348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.04503058,0.003755328,0.6946416,0.002047651,0.00356281,0.003265036,0.20072,0.00003576404,0.0004017756,0.000001970634,0.04307882,0.003458696],"study_design_scores_gemma":[0.09138031,0.04620901,0.4135342,0.03020513,0.007358354,0.0008452786,0.3332032,0.0001701105,0.003720869,0.0006311786,0.06813768,0.004604674],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9633703,0.01647358,0.000003197751,0.00439731,0.01180205,0.003478652,0.0001562608,0.00005623074,0.0002624332],"genre_scores_gemma":[0.9877872,0.002925606,0.0008780745,0.0002476069,0.006705596,0.0003668468,0.0003841433,0.00009354246,0.0006114108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2811073,"threshold_uncertainty_score":0.9996096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01257391716452887,"score_gpt":0.3047335192538736,"score_spread":0.2921596020893447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}