{"id":"W4410268611","doi":"10.1164/ajrccm.2025.211.abstracts.a1356","title":"Impact of Dupilumab on Type 2 Inflammatory Biomarkers in Patients With Chronic Obstructive Pulmonary Disease (COPD)","year":2025,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Medicine; COPD; Dupilumab; Pulmonary disease; Disease; Immunology; Internal medicine; Intensive care medicine; Asthma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001930051,0.0006454647,0.001188632,0.0001923423,0.0002208153,0.0005908138,0.0003087579,0.0005515505,0.002582374],"category_scores_gemma":[0.00249954,0.0001555567,0.001266776,0.000324797,0.0002413329,0.0004017272,0.000254154,0.0007946225,0.0002879767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003908354,"about_ca_system_score_gemma":0.0005274673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007136076,"about_ca_topic_score_gemma":0.002241763,"domain_scores_codex":[0.9989943,0.000520974,0.0001060764,0.000150924,0.0001423432,0.00008538757],"domain_scores_gemma":[0.9987161,0.0005695173,0.0003606977,0.00005009375,0.0001376519,0.0001658909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4673323,0.003784705,0.07777646,0.01070897,0.008068141,0.0002801753,0.0001283144,0.001876183,0.01572943,0.000313576,0.009008422,0.4049933],"study_design_scores_gemma":[0.1683418,0.2176886,0.5638694,0.002124963,0.01707344,0.001498784,0.0001667755,0.003752456,0.009435868,0.000642207,0.01527034,0.0001354585],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8499765,0.1362125,0.0006062437,0.001477516,0.0004181544,0.0009287182,0.003369256,0.00006961176,0.006941498],"genre_scores_gemma":[0.9896392,0.006867039,0.0005763615,0.0008873296,0.0002902681,0.0003344829,0.0009114395,0.00000595918,0.0004880983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002582374,"threshold_uncertainty_score":0.01020718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00974865267163806,"score_gpt":0.3133657837135761,"score_spread":0.303617131041938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}