{"id":"W4410270783","doi":"10.1164/ajrccm.2025.211.abstracts.a2477","title":"Oxidized Phosphatidylcholines Induce Map Kinase-dependent Production of Inflammatory Mediators in Human Airway Fibroblasts","year":2025,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Manitoba","funders":"","keywords":"Medicine; Airway; Kinase; Cell biology; Mitogen-activated protein kinase; Fibroblast; Cancer research; Immunology; In vitro; Biochemistry; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000168918,0.0003664674,0.0001618049,0.000186695,0.0001064385,0.0002038052,0.000112712,0.0002179719,0.001843118],"category_scores_gemma":[0.0001334257,0.0001346012,0.0003738038,0.0001613094,0.0001400433,0.0001520316,0.0002108625,0.0005041058,0.0005191052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001469355,"about_ca_system_score_gemma":0.000146623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005207309,"about_ca_topic_score_gemma":0.0004928835,"domain_scores_codex":[0.9998212,0.00003465096,0.0000233534,0.00003022098,0.0000482997,0.00004221937],"domain_scores_gemma":[0.9999006,0.00003208877,0.00001525708,0.00001680149,0.00001706004,0.000018177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002742094,0.00008786697,0.0002431658,0.00006657941,0.000005376958,0.00009930071,0.00002998975,0.0000414076,0.9981238,0.00002777643,0.00006309103,0.0009373401],"study_design_scores_gemma":[0.00005034155,0.0008506021,0.006895899,0.000007542701,0.00001657249,0.0002556453,0.00005126341,0.0006829291,0.9898129,0.00003809472,0.001334106,0.000004133997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994083,0.001413339,0.001918022,0.0001148737,0.00005150392,0.00007508219,0.001013124,0.00004156904,0.001289432],"genre_scores_gemma":[0.9914857,0.001025886,0.003137858,0.00009313113,0.00003125071,0.0001596513,0.001529897,0.00000812124,0.002528701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001843118,"threshold_uncertainty_score":0.006165862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.010345356257593,"score_gpt":0.2919340977027042,"score_spread":0.2815887414451111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}