{"id":"W4410284492","doi":"10.12688/hrbopenres.14112.1","title":"Trial Protocol: OPEN: Optimising Patient Experience in head and Neck radiotherapy, A phase 3 randomised control trial comparing open versus closed face masks for patients undergoing head and neck radiotherapy.","year":2025,"lang":"en","type":"preprint","venue":"HRB Open Research","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"St. Luke's Institute of Cancer Research; Health Research Board","keywords":"Medicine; Randomized controlled trial; Radiation therapy; Head and neck; Open label; Surgery; Protocol (science); Head and neck cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007580674,0.004127072,0.005437911,0.0008095498,0.001369013,0.002500777,0.002677907,0.005859155,0.04079602],"category_scores_gemma":[0.009459803,0.001610994,0.002889904,0.000888393,0.00246715,0.002389404,0.001313071,0.004817091,0.005881849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001607947,"about_ca_system_score_gemma":0.004986139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001613002,"about_ca_topic_score_gemma":0.003113965,"domain_scores_codex":[0.9960434,0.00239049,0.0003102093,0.0004629688,0.000368805,0.0004240414],"domain_scores_gemma":[0.995407,0.001427474,0.001156055,0.0005036279,0.0004704249,0.001035556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9879577,0.00354836,0.0001174842,0.001267721,0.0002800132,0.00002789784,0.00004103044,0.0001512547,0.0004451867,0.0002113621,0.00184865,0.004103361],"study_design_scores_gemma":[0.9824772,0.01570337,0.0002259265,0.00006703875,0.00007530205,0.000006888532,0.00001162285,0.0001460878,0.00006081814,0.0001839567,0.001033227,0.000008575273],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.1470814,0.003177931,0.004055792,0.002801856,0.0042057,0.8229378,0.007974102,0.0006641698,0.00710124],"genre_scores_gemma":[0.1165069,0.001224522,0.00799497,0.003072845,0.001021945,0.8602961,0.001546159,0.00007819702,0.008258361],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04079602,"threshold_uncertainty_score":0.1364763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2879269889224531,"score_gpt":0.5383709175077642,"score_spread":0.2504439285853111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}