{"id":"W4410289573","doi":"10.1016/j.apmt.2025.102782","title":"New glutathione-triggered Zr-MOF-based drug delivery platform formation via three-step premeditated reactions: MOF-S-S-COOH topology creation","year":2025,"lang":"en","type":"article","venue":"Applied Materials Today","topic":"Metal-Organic Frameworks: Synthesis and Applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Drug delivery; Metal-organic framework; Materials science; Topology (electrical circuits); Nanotechnology; Chemistry; Engineering; Organic chemistry; Electrical engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001087255,0.0003875755,0.0002561099,0.0002027854,0.0001717131,0.0002797708,0.0004490074,0.0003808923,0.000887758],"category_scores_gemma":[0.0001347799,0.0001604185,0.0002550059,0.0001528113,0.0001493789,0.0003471928,0.000285775,0.0003222982,0.0003882208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003532479,"about_ca_system_score_gemma":0.0002637393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007543144,"about_ca_topic_score_gemma":0.001367127,"domain_scores_codex":[0.9999194,0.000006845267,0.000005616717,0.00002271705,0.00001516566,0.00003023164],"domain_scores_gemma":[0.9999632,0.00000355954,0.00001329728,0.000005587689,0.00000601188,0.000008386804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001069641,0.00003081837,0.0001414838,0.0001434163,0.00002116617,0.0001625828,0.00004537002,0.0003320889,0.9875537,0.001466688,0.0002524085,0.009743286],"study_design_scores_gemma":[0.000009574662,0.0001117144,0.0002927306,0.000002834792,0.00001170756,0.0001144127,0.000007909669,0.0007701939,0.9950365,0.00005610552,0.003576787,0.000009410322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9618128,0.002608855,0.02836301,0.0002053572,0.00009707142,0.0001901941,0.0004520327,0.0008347941,0.005435936],"genre_scores_gemma":[0.9856837,0.0006136265,0.01129598,0.00003456065,0.000007838476,0.00005317354,0.0001533728,0.00002920883,0.002128605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000887758,"threshold_uncertainty_score":0.002969801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01180171324368032,"score_gpt":0.2417665622332624,"score_spread":0.2299648489895821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}