{"id":"W4410318899","doi":"10.2196/70953","title":"Clinical Efficacy and Safety of the Herbal Prescription, HH333, in Preventing Recurrent Stroke in Patients With Ischemic Stroke Induced by Small-Vessel Disease: Protocol for Multicenter, Double-Blind, Randomized, Prospective, Pilot Clinical Trial","year":2025,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Stroke (engine); Modified Rankin Scale; Physical therapy; Clinical trial; Montreal Cognitive Assessment; Observational study; Medical prescription; Randomized controlled trial; Placebo; Internal medicine; Disease; Ischemic stroke; Alternative medicine; Ischemia; Cognitive impairment; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01609864,0.003971064,0.006705121,0.001421152,0.002468538,0.001659054,0.002259151,0.005236253,0.02157748],"category_scores_gemma":[0.01333953,0.001612827,0.003208139,0.001596258,0.002616994,0.002148882,0.001135196,0.004369718,0.004066118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001665159,"about_ca_system_score_gemma":0.008995952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006214588,"about_ca_topic_score_gemma":0.001518784,"domain_scores_codex":[0.9912047,0.005341602,0.001098213,0.0006702314,0.0008699243,0.0008153865],"domain_scores_gemma":[0.992365,0.001195627,0.001857687,0.001173347,0.00176492,0.001643532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.945963,0.02536701,0.0007555227,0.003862148,0.0007647691,0.0001118553,0.000154141,0.0005684856,0.003119225,0.0006406253,0.004609984,0.01408317],"study_design_scores_gemma":[0.9442351,0.04664869,0.001529237,0.0003480729,0.0004332681,0.00003549452,0.00003227775,0.0005492046,0.0005921632,0.0003463565,0.00520885,0.00004132758],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.02630201,0.0006949616,0.001961253,0.0004207175,0.0004300108,0.9672325,0.001528956,0.0001488685,0.00128072],"genre_scores_gemma":[0.02449846,0.0004794544,0.003914263,0.0006234626,0.000194644,0.9688634,0.0007019804,0.00001233697,0.0007120449],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02157748,"threshold_uncertainty_score":0.0851388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1895143121937139,"score_gpt":0.5241812325680177,"score_spread":0.3346669203743038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}