{"id":"W4410326279","doi":"10.3390/v17050689","title":"How HIV-1 Uses the Metabolite Inositol Hexakisphosphate to Build Its Capsid","year":2025,"lang":"en","type":"review","venue":"Viruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; Wellcome Trust","keywords":"Capsid; Metabolite; Inositol; Human immunodeficiency virus (HIV); Virology; Computational biology; Chemistry; Biology; Biochemistry; Virus; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003148222,0.0005674639,0.0006036222,0.001018487,0.0002374613,0.0009344384,0.00058605,0.00080927,0.00259092],"category_scores_gemma":[0.0003177756,0.0002873463,0.0002806377,0.0008197692,0.0003748894,0.001334526,0.0004657531,0.001642192,0.00236977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005755323,"about_ca_system_score_gemma":0.0007020914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008850406,"about_ca_topic_score_gemma":0.001592988,"domain_scores_codex":[0.999913,0.00001237134,0.00001035644,0.00001538229,0.00003620146,0.00001261903],"domain_scores_gemma":[0.9999306,0.00002464059,0.000009953612,0.000002687084,0.00002204158,0.00001003076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008953916,0.00005093314,0.0001292286,0.008453622,0.00003989032,0.0001467314,0.00005774134,0.0003577166,0.004167622,0.006806082,0.04051657,0.9391844],"study_design_scores_gemma":[0.00001000626,0.00005253618,0.0002874176,0.0008488777,0.00002272534,0.0005243715,0.00002829626,0.0000585989,0.0006724169,0.001271102,0.9962147,0.000009005229],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002208711,0.9962841,0.0001875996,0.0004900756,0.0005667604,0.000007014664,0.00002252288,0.00001312828,0.002207961],"genre_scores_gemma":[0.0008092269,0.9974174,0.0001498972,0.0002614598,0.0001799271,0.000006444352,0.00003102261,0.000001709881,0.001142919],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00259092,"threshold_uncertainty_score":0.008667529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05537631459351763,"score_gpt":0.3498341573979865,"score_spread":0.2944578428044689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}