{"id":"W4410343518","doi":"10.1016/j.vaccine.2025.127131","title":"Clinical and regulatory development strategies for GBS vaccines intended for maternal immunisation in low- and middle-income countries","year":2025,"lang":"en","type":"article","venue":"Vaccine","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"European Medicines Agency; World Health Organization; Bill and Melinda Gates Foundation","keywords":"Low and middle income countries; Medicine; Pregnancy; Environmental health; Immunology; Developing country; Economic growth; Biology; Economics; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1032492,0.001397433,0.0007813065,0.0026606,0.002504558,0.01139544,0.004186274,0.01420572,0.0115821],"category_scores_gemma":[0.06910936,0.0007780826,0.00148424,0.001397917,0.004132618,0.006273049,0.006719484,0.008993271,0.002690766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007822196,"about_ca_system_score_gemma":0.0709277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00433892,"about_ca_topic_score_gemma":0.005582124,"domain_scores_codex":[0.948686,0.03151836,0.003844872,0.002683648,0.007877699,0.005389392],"domain_scores_gemma":[0.9509069,0.01461269,0.00651441,0.00182115,0.01796199,0.008182894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001002817,0.001349301,0.009212117,0.005762714,0.0001130046,0.003745947,0.005223949,0.006031143,0.01935313,0.2126899,0.2326757,0.5028403],"study_design_scores_gemma":[0.0004896072,0.002152039,0.008703613,0.007459704,0.0001237681,0.001423819,0.004227794,0.00325113,0.007376253,0.04580118,0.9188436,0.0001474824],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.02431848,0.08280547,0.03725213,0.7357781,0.009552886,0.006725552,0.0006817533,0.00056586,0.1023199],"genre_scores_gemma":[0.3469035,0.07606962,0.149082,0.3642405,0.009229979,0.01045688,0.001685043,0.0002495175,0.04208299],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.1032492,"threshold_uncertainty_score":0.5460404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01879965756368826,"score_gpt":0.2945019757663339,"score_spread":0.2757023182026456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}