{"id":"W4410368075","doi":"10.3390/curroncol32050278","title":"Mechanistic Insights and Future Directions for Enfortumab Vedotin in Urothelial Carcinoma: Highlights from the 10th Annual Leo &amp; Anne Albert Institute for Bladder Cancer Care and Research Symposium","year":2025,"lang":"en","type":"review","venue":"Current Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Bladder cancer; Pembrolizumab; Clinical trial; Oncology; Internal medicine; Disease; Cancer; Urothelial cancer; Urothelial carcinoma; Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001115581,0.0005470252,0.001017388,0.001172545,0.0002426589,0.001366206,0.0006831836,0.001001874,0.005447162],"category_scores_gemma":[0.000829394,0.0002094493,0.0008198984,0.001071297,0.0003637999,0.001707901,0.0007805281,0.002210192,0.001726995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005972796,"about_ca_system_score_gemma":0.001468946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008193237,"about_ca_topic_score_gemma":0.002506299,"domain_scores_codex":[0.9998393,0.00004324481,0.00002126761,0.00002352887,0.00004598183,0.00002672239],"domain_scores_gemma":[0.9996998,0.0001199005,0.00003911018,0.000008950133,0.00009756583,0.00003460977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002655796,0.0001318374,0.0001505192,0.02196612,0.0001537629,0.0002307262,0.000111524,0.0004971779,0.002939071,0.009388811,0.08232917,0.8818358],"study_design_scores_gemma":[0.0000429644,0.0001774931,0.0004161269,0.004301833,0.0001571999,0.0004186411,0.00006579513,0.00009469721,0.0004274248,0.002748285,0.991133,0.00001640056],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001277519,0.9975744,0.00008542622,0.001145657,0.0004095543,0.000006372992,0.0000301442,0.000006101734,0.0006145833],"genre_scores_gemma":[0.0007166102,0.9977279,0.0001219931,0.0005858446,0.0002729071,0.000008692163,0.00004229075,0.000001520844,0.0005222985],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005447162,"threshold_uncertainty_score":0.01822251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1172378783594064,"score_gpt":0.4553304150399648,"score_spread":0.3380925366805584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}