{"id":"W4410369225","doi":"10.1177/2050313x251341561","title":"Successful treatment of localized scleroderma using brodalumab: A case report","year":2025,"lang":"en","type":"article","venue":"SAGE Open Medical Case Reports","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Medicine; Methotrexate; Scleroderma (fungus); Refractory (planetary science); Nintedanib; Pathogenesis; Autoimmune disease; Dermatology; Immunology; Disease; Internal medicine; Idiopathic pulmonary fibrosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001142795,0.0003015138,0.001127985,0.0001961004,0.0002046813,0.00005979273,0.00009055351,0.0003624369,0.001701035],"category_scores_gemma":[0.001356495,0.0002140812,0.0003285699,0.0005774863,0.0002616606,0.0001132552,0.0002093634,0.0001718981,0.00000380245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002931761,"about_ca_system_score_gemma":0.002140291,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01470449,"about_ca_topic_score_gemma":0.0002424832,"domain_scores_codex":[0.996049,0.0001860223,0.001841893,0.0007375863,0.0008148435,0.0003706357],"domain_scores_gemma":[0.9970294,0.0001718685,0.0006332368,0.001209166,0.0002377923,0.0007185061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001838386,0.0009533118,0.01306632,0.00025067,0.0004800312,0.9523234,0.0001339354,0.000007016772,0.0003610304,0.000008170954,0.0007222899,0.03150997],"study_design_scores_gemma":[0.003576938,0.0001962233,0.0005207477,0.004196223,0.001170898,0.9836,0.0009426464,0.0009581345,0.002025275,0.00003701818,0.002589313,0.0001866049],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814486,0.008259541,0.0005581895,0.000472299,0.0007192053,0.001665756,0.0000131072,0.0000597811,0.006803512],"genre_scores_gemma":[0.9966037,0.0004493995,0.0004995628,0.000289092,0.00013449,0.00007823668,0.00004446182,0.00003187355,0.001869201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03132337,"threshold_uncertainty_score":0.9992115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04142681054010632,"score_gpt":0.3680991657504918,"score_spread":0.3266723552103855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}