{"id":"W4410393769","doi":"10.1371/journal.pone.0323227","title":"Leishmania regulates host YY1: Comparative proteomic analysis identifies infection modulated YY1 dependent proteins","year":2025,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Genome British Columbia","keywords":"Biology; Leishmania; Leishmania major; YY1; Cell biology; Cytoplasm; Virology; Parasite hosting; Gene; Genetics; Gene expression; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009847683,0.0002578584,0.0001999206,0.0001915797,0.0001262906,0.0002323492,0.000108482,0.0001686989,0.0009078727],"category_scores_gemma":[0.00009863153,0.00009540227,0.0002458453,0.000167725,0.0001110464,0.0002107116,0.0001872446,0.0002498406,0.0003108727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001590574,"about_ca_system_score_gemma":0.0001271842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000307746,"about_ca_topic_score_gemma":0.0003690288,"domain_scores_codex":[0.9999489,0.000006884935,0.000003607842,0.00001401129,0.00001072335,0.00001590776],"domain_scores_gemma":[0.9999514,0.000006800225,0.00001350329,0.000003110663,0.00001008572,0.00001515684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009735428,0.000004385572,0.0002222301,0.00003137599,0.000003767685,0.00003228278,0.000008437891,0.00001013723,0.9991595,0.00002560746,0.00002229543,0.0003826096],"study_design_scores_gemma":[0.00001670094,0.0002950657,0.05798128,0.00001605502,0.00005101057,0.000935004,0.00010799,0.001358264,0.9339111,0.00009333562,0.005218665,0.00001549261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912041,0.003427537,0.002984561,0.0001030983,0.00002990841,0.00002431812,0.001387606,0.00003259721,0.0008061921],"genre_scores_gemma":[0.988231,0.00222902,0.004133928,0.0001292936,0.00001769224,0.00003683526,0.003005982,0.00003544981,0.002180783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009078727,"threshold_uncertainty_score":0.003037095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05898936534239599,"score_gpt":0.311880238657212,"score_spread":0.252890873314816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}