{"id":"W4410403206","doi":"10.1128/aac.00296-25","title":"<i>In vitro</i> activity of gepotidacin against urinary tract infection isolates of Enterobacterales, <i>Enterococcus faecalis</i> , and <i>Staphylococcus saprophyticus</i>","year":2025,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Urinary Tract Infections Management","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Staphylococcus saprophyticus; Microbiology; Enterococcus faecalis; Enterobacter cloacae; Klebsiella pneumoniae; Providencia; Biology; Enterococcus faecium; Klebsiella oxytoca; Broth microdilution; Enterobacter; Enterobacter aerogenes; Proteus mirabilis; Enterococcus; Ciprofloxacin; Staphylococcus aureus; Minimum inhibitory concentration; Escherichia coli; Staphylococcus epidermidis; Antibiotics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003215567,0.0004185857,0.0003134156,0.0002887578,0.0001123255,0.0002790771,0.0002432433,0.0002654079,0.001281861],"category_scores_gemma":[0.000640988,0.0001582271,0.0002650427,0.0003505248,0.0001514969,0.0001968114,0.0002580514,0.0003402613,0.0002277851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002024791,"about_ca_system_score_gemma":0.0002431515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002056775,"about_ca_topic_score_gemma":0.002629376,"domain_scores_codex":[0.9995234,0.0001726096,0.0000688033,0.00006916447,0.0001081978,0.00005792702],"domain_scores_gemma":[0.9996581,0.0001026931,0.00006911391,0.00002228272,0.00009795713,0.0000498443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002312873,0.0004798565,0.003909614,0.0003219645,0.00005108024,0.0000889569,0.0000676569,0.001035282,0.983736,0.00004298599,0.0002780058,0.00767561],"study_design_scores_gemma":[0.0002057079,0.0211458,0.04225618,0.0000723956,0.0001119123,0.0007737793,0.0001250886,0.002433058,0.9307278,0.00003919793,0.002086462,0.00002249583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953083,0.001483312,0.0006376363,0.00004935979,0.00002290871,0.00006159861,0.001076602,0.00002873056,0.001331525],"genre_scores_gemma":[0.9942174,0.0008090923,0.001787242,0.00005168597,0.00001562457,0.00003959961,0.002322542,0.000008968279,0.0007477441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002056775,"threshold_uncertainty_score":0.004288256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007825972231894853,"score_gpt":0.2515797924239976,"score_spread":0.2437538201921027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}