{"id":"W4410403206","doi":"10.1128/aac.00296-25","title":"<i>In vitro</i> activity of gepotidacin against urinary tract infection isolates of Enterobacterales, <i>Enterococcus faecalis</i> , and <i>Staphylococcus saprophyticus</i>","year":2025,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Urinary Tract Infections Management","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Staphylococcus saprophyticus; Microbiology; Enterococcus faecalis; Enterobacter cloacae; Klebsiella pneumoniae; Providencia; Biology; Enterococcus faecium; Klebsiella oxytoca; Broth microdilution; Enterobacter; Enterobacter aerogenes; Proteus mirabilis; Enterococcus; Ciprofloxacin; Staphylococcus aureus; Minimum inhibitory concentration; Escherichia coli; Staphylococcus epidermidis; Antibiotics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001220588,0.000248429,0.0005169114,0.0003153259,0.00005688219,0.00002083026,0.00005838817,0.0001110353,0.00001759139],"category_scores_gemma":[0.000005826418,0.0002323142,0.0001266661,0.0002807335,0.000149452,0.0002232034,0.00006436709,0.0001928764,8.745657e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004994751,"about_ca_system_score_gemma":0.00002811026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002785188,"about_ca_topic_score_gemma":0.000007629267,"domain_scores_codex":[0.9988599,0.00004925873,0.0004235163,0.0003462024,0.00009031704,0.0002308167],"domain_scores_gemma":[0.9994144,0.00003245822,0.0001986703,0.0002424402,0.00005664894,0.00005534267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001367797,0.007429986,0.2051537,0.001016785,0.0002206815,0.00002848233,0.0001942432,0.000006407245,0.7754534,0.00001302041,0.002017259,0.007098259],"study_design_scores_gemma":[0.005334463,0.001136774,0.3746701,0.0005165896,0.0001216482,0.00004780726,0.00001620582,0.0001031158,0.6029111,0.00002742256,0.01489989,0.0002149521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965028,0.00007729398,0.0001482147,0.00161113,0.000155297,0.0006616043,0.00003253647,0.00002721373,0.0007838881],"genre_scores_gemma":[0.9931395,0.002905462,0.0001580761,0.003405453,0.00003665815,0.00001312359,0.00001557803,0.00002102083,0.0003050983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1725424,"threshold_uncertainty_score":0.94735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007825972231894853,"score_gpt":0.2515797924239976,"score_spread":0.2437538201921027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}