{"id":"W4410404215","doi":"10.1128/aac.00137-25","title":"Antibiofilm activity of manogepix, ibrexafungerp, amphotericin B, rezafungin, and caspofungin against <i>Candida</i> spp. biofilms of reference and clinical strains","year":2025,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biofilm; Caspofungin; Microbiology; Amphotericin B; Biology; Corpus albicans; Candida albicans; Minimum inhibitory concentration; Candida parapsilosis; Antimicrobial; In vitro; Bacteria; Antifungal; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001997672,0.0003494609,0.0002950899,0.00024721,0.0001061401,0.0002477199,0.0001831695,0.0002299568,0.0005422364],"category_scores_gemma":[0.0002249582,0.0001138185,0.0002264963,0.0001765225,0.0001235356,0.0001626305,0.0002842975,0.0002002134,0.00008300582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001432207,"about_ca_system_score_gemma":0.0002018613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001044026,"about_ca_topic_score_gemma":0.001345234,"domain_scores_codex":[0.999772,0.00004512066,0.00002440029,0.00004358729,0.00008461043,0.00003022165],"domain_scores_gemma":[0.9999098,0.00001778601,0.00002941863,0.000006020589,0.0000219282,0.00001499942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004259872,0.00007959288,0.003963424,0.0001186366,0.0000250183,0.00007786547,0.00005276465,0.0001092592,0.9876472,0.00001762283,0.00006351747,0.007419248],"study_design_scores_gemma":[0.00007336153,0.008343665,0.1128728,0.00005464384,0.000176621,0.0009642994,0.0002602398,0.0009542123,0.8727067,0.00002182663,0.003551242,0.00002031275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997122,0.002106705,0.0001622024,0.00002953361,0.000008111117,0.00002674197,0.0001534649,0.00000852975,0.0003826443],"genre_scores_gemma":[0.9962897,0.001458518,0.001343023,0.00004371365,0.000008023345,0.00001885751,0.0002969615,0.000003181235,0.0005380584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001044026,"threshold_uncertainty_score":0.002075911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01997164311174092,"score_gpt":0.3176851957395196,"score_spread":0.2977135526277787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}