{"id":"W4410479686","doi":"10.1111/cas.70097","title":"Clonal Hematopoiesis and Solid Cancers","year":2025,"lang":"en","type":"review","venue":"Cancer Science","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"Japan Agency for Medical Research and Development; Japan Society for the Promotion of Science; Leukemia and Lymphoma Society of Canada; Moonshot Research and Development Program; Leukemia and Lymphoma Society","keywords":"Haematopoiesis; Somatic evolution in cancer; Biology; Somatic cell; Carcinogenesis; Germline mutation; Cancer; Germline; Cancer research; Immunology; Stem cell; Mutation; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004721417,0.0006263547,0.0008854167,0.002063666,0.0002921693,0.0009701401,0.0006405355,0.001097608,0.003237628],"category_scores_gemma":[0.0008547099,0.0002044439,0.0003832476,0.001718745,0.0006206384,0.001233127,0.0007560264,0.001835087,0.001694792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007626133,"about_ca_system_score_gemma":0.001212842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001100599,"about_ca_topic_score_gemma":0.001878873,"domain_scores_codex":[0.9997804,0.00003725815,0.000027642,0.00003672406,0.00009349571,0.00002454255],"domain_scores_gemma":[0.9996152,0.0001886804,0.00005070413,0.00001210028,0.00009479701,0.00003843406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005195306,0.00003399726,0.0002560121,0.01060873,0.00006564051,0.000218129,0.0000660953,0.0003260142,0.001185118,0.007352489,0.04458862,0.9352472],"study_design_scores_gemma":[0.000007490034,0.00004435272,0.0007313399,0.002681977,0.00004551632,0.001486424,0.00004362476,0.00005723199,0.000241476,0.003118955,0.9915311,0.00001060238],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007993365,0.998226,0.0000796555,0.0003076679,0.0002409229,0.000002169865,0.00001013176,0.000005865886,0.00104767],"genre_scores_gemma":[0.0007537084,0.998026,0.000092396,0.0002574412,0.0002465651,0.00000322221,0.00002477788,0.000001250254,0.0005946897],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003237628,"threshold_uncertainty_score":0.01083094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05538512062537605,"score_gpt":0.4524089969687432,"score_spread":0.3970238763433672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}