{"id":"W4410505147","doi":"10.1080/07366205.2025.2505347","title":"Integration of mass cytometry and single-cell RNA-sequencing of cells in bronchoalveolar lavage","year":2025,"lang":"en","type":"article","venue":"BioTechniques","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Mitacs; Canadian Institutes of Health Research; Genome British Columbia; Michael Smith Health Research BC","keywords":"RNA; Molecular biology; Bronchoalveolar lavage; Biology; Cell; Gene expression; Population; Flow cytometry; Gene; Genetics; Medicine; Lung","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001813746,0.0001035171,0.0001682448,0.0001630691,0.00001414767,0.000008107106,0.0001080857,0.000243033,0.000002166876],"category_scores_gemma":[0.0000306941,0.0001016483,0.00005043876,0.000139956,0.00008679706,0.000004716319,0.0000347254,0.00009290907,1.090356e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002472974,"about_ca_system_score_gemma":0.00004742276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001892504,"about_ca_topic_score_gemma":0.00004527904,"domain_scores_codex":[0.9993391,0.00004132076,0.0002678238,0.00018767,0.00006081911,0.0001032424],"domain_scores_gemma":[0.9996518,0.00001413149,0.00008473689,0.0001775422,0.0000528561,0.00001891659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004325603,0.00005923214,0.001178712,0.0001106974,0.000007257969,6.494037e-7,0.0000485974,0.000002134387,0.9953622,0.00006765273,0.00007009377,0.003049538],"study_design_scores_gemma":[0.0002158094,0.0002203544,0.0003605479,0.0001183222,0.000009437835,3.685578e-7,0.00005789518,0.00005505994,0.9981137,0.0001526653,0.0006091411,0.00008668387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9117755,0.0009237952,0.08493964,0.00002312264,0.00005356281,0.0001571382,0.00001662928,0.00001545509,0.0020951],"genre_scores_gemma":[0.9817718,0.0005211271,0.0174743,0.00005087612,0.00001489424,0.000004270874,0.00001579307,0.000009067888,0.0001379105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0699962,"threshold_uncertainty_score":0.4145098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0130005663587106,"score_gpt":0.2393388515769691,"score_spread":0.2263382852182585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}