{"id":"W4410512971","doi":"10.3899/jrheum.2025-0390.o025","title":"RESULTS FROM THE REGENCY TRIAL ASSESSING EFFICACY AND SAFETY OF OBINUTUZUMAB IN ACTIVE LUPUS NEPHRITIS","year":2025,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"","keywords":"Medicine; Obinutuzumab; Lupus nephritis; Internal medicine; Rituximab; Lymphoma; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006931968,0.001061247,0.002164058,0.0002774201,0.000439957,0.001405853,0.0006569483,0.001627063,0.008037942],"category_scores_gemma":[0.005763845,0.0003037254,0.001956541,0.000310575,0.000857702,0.000884017,0.0004636594,0.002763527,0.0009781488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005970456,"about_ca_system_score_gemma":0.000843934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005437127,"about_ca_topic_score_gemma":0.001304133,"domain_scores_codex":[0.9975504,0.001779291,0.0001199922,0.0002026417,0.0001876281,0.0001599835],"domain_scores_gemma":[0.9957986,0.001861619,0.0009742743,0.0003347266,0.0002811755,0.000749507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9667023,0.001880215,0.002357732,0.00103283,0.001952327,0.00006029378,0.00008112858,0.0003362356,0.00180651,0.0002710625,0.005798794,0.01772055],"study_design_scores_gemma":[0.9064858,0.07103305,0.01303868,0.000236453,0.002423203,0.0001429214,0.00004997989,0.0004133452,0.0007999211,0.000442713,0.004901368,0.00003259283],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9468697,0.02278678,0.0007230435,0.002693224,0.0009299485,0.004764972,0.006914852,0.0001377745,0.01417979],"genre_scores_gemma":[0.9736668,0.004740381,0.001107992,0.002788635,0.001180587,0.003496119,0.006540509,0.00004455815,0.00643432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008037942,"threshold_uncertainty_score":0.03666025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02520746196099016,"score_gpt":0.3281786458541908,"score_spread":0.3029711838932006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}