{"id":"W4410513149","doi":"10.3899/jrheum.2025-0390.pv181","title":"LOW-DOSE INTERLEUKIN-2 THERAPY IN ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS (LUPIL-2): A MULTICENTER, DOUBLE-BLIND, RANDOMIZED AND PLACEBO-CONTROLLED PHASE 2 TRIAL","year":2025,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Double blind; Randomized controlled trial; Internal medicine; Lupus erythematosus; Physical therapy; Immunology; Pathology; Alternative medicine; Antibody","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002956216,0.002013326,0.002762117,0.0005155742,0.0005125068,0.001115393,0.000812266,0.002358368,0.005512687],"category_scores_gemma":[0.001542542,0.0005905216,0.001345119,0.0003784872,0.001225396,0.001106004,0.0003890086,0.00202532,0.0008445792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004519683,"about_ca_system_score_gemma":0.0009818485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001810272,"about_ca_topic_score_gemma":0.0004171215,"domain_scores_codex":[0.9990814,0.0005331709,0.00004813883,0.0001663853,0.00007034114,0.0001005019],"domain_scores_gemma":[0.9992962,0.0001784723,0.0001821181,0.00005913455,0.00005611292,0.0002279789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9675484,0.009862816,0.000493739,0.0006167135,0.0005111576,0.00004595404,0.00003960349,0.0001643968,0.005985552,0.0001285637,0.0007448767,0.01385819],"study_design_scores_gemma":[0.9476958,0.05061038,0.0005668715,0.00001786317,0.0001737141,0.00002350138,0.000006241045,0.0001562517,0.0003265064,0.00006676875,0.0003488448,0.000007245733],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978707,0.006722641,0.001729716,0.001120705,0.0008062682,0.007753957,0.001071968,0.0002417112,0.001845948],"genre_scores_gemma":[0.967767,0.00410442,0.005055232,0.002558633,0.001176929,0.01414067,0.001465813,0.00004575018,0.003685652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005512687,"threshold_uncertainty_score":0.0184418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02644685731479818,"score_gpt":0.3455274633761829,"score_spread":0.3190806060613847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}