{"id":"W4410513227","doi":"10.3899/jrheum.2025-0390.o012","title":"ACHIEVEMENT OF PROTEINURIA LESS THAN 0.4 G/G IN THE PHASE 3 AURORA 1 STUDY OF VOCLOSPORIN IN LUPUS NEPHRITIS","year":2025,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Medicine; Lupus nephritis; Proteinuria; Nephritis; Internal medicine; Immunology; Kidney; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00407645,0.001077594,0.002338573,0.0002978906,0.0004802911,0.001062596,0.0006087135,0.001259719,0.004274949],"category_scores_gemma":[0.001942774,0.0004784081,0.002020937,0.0003065185,0.0006890972,0.000613224,0.0004335197,0.002732998,0.0005501728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005051064,"about_ca_system_score_gemma":0.00152567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000623402,"about_ca_topic_score_gemma":0.002427071,"domain_scores_codex":[0.9984289,0.001106672,0.00007212008,0.0001159971,0.00009171222,0.0001844959],"domain_scores_gemma":[0.9986672,0.0003428529,0.0003653347,0.0000765687,0.00007390416,0.0004740109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.959565,0.008510626,0.002013102,0.0007155658,0.001765401,0.00005711356,0.00009762526,0.0004078802,0.004819874,0.0001248016,0.001385802,0.02053712],"study_design_scores_gemma":[0.672037,0.3097442,0.01240103,0.00009457556,0.001968377,0.00007820076,0.00004929643,0.0004554303,0.001017026,0.000291781,0.001827137,0.00003597394],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859999,0.006118233,0.0004747427,0.0008581853,0.0003149124,0.002686839,0.000880302,0.00007992076,0.002587103],"genre_scores_gemma":[0.9914164,0.001991769,0.000822761,0.0008673306,0.0003088171,0.002324746,0.0004647561,0.00001803545,0.001785391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004274949,"threshold_uncertainty_score":0.02155858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03079786565622822,"score_gpt":0.3464042714156826,"score_spread":0.3156064057594544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}