{"id":"W4410513358","doi":"10.1007/978-3-031-85519-1_19","title":"Biomarkers of Neuroprogression","year":2025,"lang":"en","type":"book-chapter","venue":"","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"History","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003113757,0.0007923031,0.0005021689,0.001202068,0.0001889786,0.001127138,0.0005181306,0.00104866,0.01716712],"category_scores_gemma":[0.0003758898,0.0002222722,0.0002767789,0.0007342761,0.0003881103,0.0009967786,0.0005843115,0.001019423,0.01454807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003549712,"about_ca_system_score_gemma":0.0002235777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003782526,"about_ca_topic_score_gemma":0.001107361,"domain_scores_codex":[0.9998556,0.00002644759,0.000007256244,0.00002759777,0.00007215796,0.00001088517],"domain_scores_gemma":[0.9999199,0.00004503786,0.000006139912,0.000006384078,0.00001583675,0.000006606302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001158556,0.00008080235,0.0004657881,0.0007794091,0.00003501077,0.0004979026,0.00008282761,0.0003700525,0.02947221,0.05283459,0.1769427,0.738323],"study_design_scores_gemma":[0.000007633167,0.0001075105,0.001163565,0.0003115604,0.00001745562,0.002170872,0.00005483332,0.0004962362,0.01380266,0.03098712,0.9508566,0.00002391391],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004413132,0.5220951,0.04869001,0.008594124,0.01010314,0.0001141294,0.001444923,0.0007640299,0.4037815],"genre_scores_gemma":[0.02115568,0.1485743,0.02003147,0.004368916,0.0035905,0.0001663557,0.001007141,0.000144061,0.8009616],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01716712,"threshold_uncertainty_score":0.05742973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02487866314605516,"score_gpt":0.2605666649068124,"score_spread":0.2356880017607572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}