{"id":"W4410542638","doi":"10.3390/biomedicines13051248","title":"Systemic Ozone Therapy Improves Oral Hard and Soft Tissue Healing in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Study in Senescent Female Rats","year":2025,"lang":"en","type":"article","venue":"Biomedicines","topic":"Bone health and treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Osteonecrosis of the jaw; Ozone therapy; Medicine; Soft tissue; Bisphosphonate; Saline; Bisphosphonate-associated osteonecrosis of the jaw; Dental alveolus; Bone healing; Dentistry; Internal medicine; Surgery; Pathology; Osteoporosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002788042,0.0006324457,0.0005791115,0.0005761102,0.0002978917,0.0002212961,0.0002439254,0.0003862641,0.001251481],"category_scores_gemma":[0.0001300357,0.0002408455,0.0007079719,0.0001804668,0.0003481438,0.0003871745,0.0002560198,0.0008994888,0.0002314846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001704976,"about_ca_system_score_gemma":0.0003998913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000687703,"about_ca_topic_score_gemma":0.001657533,"domain_scores_codex":[0.9998472,0.00001421838,0.0000151544,0.00003329438,0.00004549726,0.00004463893],"domain_scores_gemma":[0.9997632,0.00001180721,0.00007656105,0.00002057912,0.0000430872,0.00008481117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003506693,0.004252164,0.004166503,0.0001920732,0.00004155824,0.0003659744,0.0001231201,0.00005775956,0.9794213,0.00007972112,0.0001166882,0.007676527],"study_design_scores_gemma":[0.001214206,0.1649203,0.1537553,0.00008367441,0.0005757765,0.002583357,0.001875637,0.001262186,0.6665244,0.0003076134,0.006814259,0.00008333461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982038,0.001033929,0.0003312458,0.00004563476,0.00003137403,0.00003373446,0.00009192638,0.00001083605,0.0002175139],"genre_scores_gemma":[0.9901696,0.003737104,0.001465359,0.0001642691,0.00003737471,0.0001414988,0.0004253375,0.00001172218,0.003847705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001251481,"threshold_uncertainty_score":0.00418663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02404714597283557,"score_gpt":0.3321147892510992,"score_spread":0.3080676432782636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}